Endothelial and Vascular Health: A Tale of Honey, HO and Calcium

Overview

Journal Cells

Publisher MDPI

Specialties Biochemistry
Biophysics
Cell Biology
Molecular Biology

Date 2021 May 5

PMID 33946572

Citations 2

Authors

Elia Ranzato

Gregorio Bonsignore

Mauro Patrone

Simona Martinotti

Affiliations

Soon will be listed here.

Abstract

Intracellular Ca regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells' responses and the central role played by Ca signaling as an encouraging target for more efficacious clinical treatments.

Citing Articles

Correlation between Honey Parameters and Wound Healing Properties: The Case of Piedmont (Italy) Samples.

Martinotti S, Bonsignore G, Patrone M, Ranzato E Curr Pharm Biotechnol. 2024; 26(2):302-311.

PMID: 39238381 DOI: 10.2174/0113892010328741240828093859.

ER Stress Response and Induction of Apoptosis in Malignant Pleural Mesothelioma: The Achilles Heel Targeted by the Anticancer Ruthenium Drug BOLD-100.

Ranzato E, Bonsignore G, Martinotti S Cancers (Basel). 2022; 14(17).

PMID: 36077664 PMC: 9454852. DOI: 10.3390/cancers14174126.

Reactive Oxygen Species and Endothelial Ca Signaling: Brothers in Arms or Partners in Crime?.

Negri S, Faris P, Moccia F Int J Mol Sci. 2021; 22(18).

PMID: 34575985 PMC: 8465413. DOI: 10.3390/ijms22189821.

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