Seroprevalence of Among Sylvatic Rodents in Poland

Overview

Journal Animals (Basel)

Date 2021 Apr 30

PMID 33917803

Citations 6

Authors

Maciej Grzybek

Daniela Antolova

Katarzyna Tolkacz

Mohammed Alsarraf

Jolanta Behnke-Borowczyk

Joanna Nowicka

Jerzy Paleolog

Beata Biernat

Jerzy M Behnke

Anna Bajer

Affiliations

Soon will be listed here.

Abstract

is an intracellular Apicomplexan parasite with a broad range of intermediate hosts, including humans and rodents. Rodents are considered to be reservoirs of infection for their predators, including cats, felids, pigs, and wild boars. We conducted a multi-site, long-term study on in northeastern Poland. The study aimed to monitor the seroprevalence of in the four abundant vole species found in the region (, and ) and to assess the influence of both extrinsic (year of study and study site) and intrinsic (host sex and host age) factors on seroprevalence. A bespoke enzyme-linked immunosorbent assay was used to detect antibodies against . We examined 577 rodent individuals and detected antibodies in the sera of all four rodent species with an overall seroprevalence of 5.5% [4.2-7.3] (3.6% [2.6-4.9] for and 20% [12-30.9] for , , and ). Seroprevalence in bank voles varied significantly between host age and sex. Seroprevalence increased with host age and was higher in females than males. These results contribute to our understanding of the distribution and abundance of in voles in Poland and confirm that also circulates in and , and . Therefore, they may potentially play a role as reservoirs of this parasite in the sylvatic environment.

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References

Grzybek M, Sironen T, Maki S, Tolkacz K, Alsarraf M, Strachecka A . Zoonotic Virus Seroprevalence among Bank Voles, Poland, 2002-2010. Emerg Infect Dis. 2019; 25(8):1607-1609. PMC: 6649315. DOI: 10.3201/eid2508.190217. View

Tolkacz K, Bednarska M, Alsarraf M, Dwuznik D, Grzybek M, Welc-Faleciak R . Prevalence, genetic identity and vertical transmission of Babesia microti in three naturally infected species of vole, Microtus spp. (Cricetidae). Parasit Vectors. 2017; 10(1):66. PMC: 5294907. DOI: 10.1186/s13071-017-2007-x. View

Afonso E, Thulliez P, Pontier D, Gilot-Fromont E . Toxoplasmosis in prey species and consequences for prevalence in feral cats: not all prey species are equal. Parasitology. 2007; 134(Pt.14):1963-71. DOI: 10.1017/S0031182007003320. View

Achazi K, Ruzek D, Donoso-Mantke O, Schlegel M, Ali H, Wenk M . Rodents as sentinels for the prevalence of tick-borne encephalitis virus. Vector Borne Zoonotic Dis. 2011; 11(6):641-7. PMC: 3115460. DOI: 10.1089/vbz.2010.0236. View

Grzybek M, Alsarraf M, Tolkacz K, Behnke-Borowczyk J, Biernat B, Stanczak J . Seroprevalence of TBEV in bank voles from Poland-a long-term approach. Emerg Microbes Infect. 2018; 7(1):145. PMC: 6092418. DOI: 10.1038/s41426-018-0149-3. View

Naguleswaran A, Hemphill A, Rajapakse R, Sager H . Elaboration of a crude antigen ELISA for serodiagnosis of caprine neosporosis: validation of the test by detection of Neospora caninum-specific antibodies in goats from Sri Lanka. Vet Parasitol. 2004; 126(3):257-62. DOI: 10.1016/j.vetpar.2004.08.014. View

Thompson R, Lymbery A, Smith A . Parasites, emerging disease and wildlife conservation. Int J Parasitol. 2010; 40(10):1163-70. DOI: 10.1016/j.ijpara.2010.04.009. View

Grzybek M, Cybulska A, Tolkacz K, Alsarraf M, Behnke-Borowczyk J, Szczepaniak K . Seroprevalence of spp. infection in bank voles () - A long term study. Int J Parasitol Parasites Wildl. 2019; 9:144-148. PMC: 6524169. DOI: 10.1016/j.ijppaw.2019.03.005. View

Mercier A, Garba M, Bonnabau H, Kane M, Rossi J, Darde M . Toxoplasmosis seroprevalence in urban rodents: a survey in Niamey, Niger. Mem Inst Oswaldo Cruz. 2013; 108(4):399-407. PMC: 3970615. DOI: 10.1590/S0074-0276108042013002. View

10.

Lehrer E, Fredebaugh S, Schooley R, Mateus-Pinilla N . Prevalence of antibodies to Toxoplasma gondii in woodchucks across an urban-rural gradient. J Wildl Dis. 2010; 46(3):977-80. DOI: 10.7589/0090-3558-46.3.977. View

11.

Tenter A, Heckeroth A, Weiss L . Toxoplasma gondii: from animals to humans. Int J Parasitol. 2000; 30(12-13):1217-58. PMC: 3109627. DOI: 10.1016/s0020-7519(00)00124-7. View

12.

Opsteegh M, Teunis P, Mensink M, Zuchner L, Titilincu A, Langelaar M . Evaluation of ELISA test characteristics and estimation of Toxoplasma gondii seroprevalence in Dutch sheep using mixture models. Prev Vet Med. 2010; 96(3-4):232-40. DOI: 10.1016/j.prevetmed.2010.06.009. View

13.

Hughes H, van Knapen F, Atkinson H, Balfour A, Lee D . A new soluble antigen preparation of Toxoplasma gondii and its use in serological diagnosis. Clin Exp Immunol. 1982; 49(1):239-46. PMC: 1536634. View

14.

Afonso E, Poulle M, Lemoine M, Villena I, Aubert D, Gilot-Fromont E . Prevalence of Toxoplasma gondii in small mammals from the Ardennes region, France. Folia Parasitol (Praha). 2008; 54(4):313-4. DOI: 10.14411/fp.2007.041. View

15.

Johnson H, Koshy A . Latent Toxoplasmosis Effects on Rodents and Humans: How Much is Real and How Much is Media Hype?. mBio. 2020; 11(2). PMC: 7078474. DOI: 10.1128/mBio.02164-19. View

16.

Ding H, Gao Y, Deng Y, Lamberton P, Lu D . A systematic review and meta-analysis of the seroprevalence of Toxoplasma gondii in cats in mainland China. Parasit Vectors. 2017; 10(1):27. PMC: 5237326. DOI: 10.1186/s13071-017-1970-6. View

17.

Hill D, Dubey J . Toxoplasma gondii: transmission, diagnosis and prevention. Clin Microbiol Infect. 2002; 8(10):634-40. DOI: 10.1046/j.1469-0691.2002.00485.x. View

18.

Reperant L, Hegglin D, Tanner I, Fischer C, Deplazes P . Rodents as shared indicators for zoonotic parasites of carnivores in urban environments. Parasitology. 2009; 136(3):329-37. DOI: 10.1017/S0031182008005428. View

19.

Behnke J, Barnard C, Bajer A, Bray D, Dinmore J, Frake K . Variation in the helminth community structure in bank voles (Clethrionomys glareolus) from three comparable localities in the Mazury Lake District region of Poland. Parasitology. 2001; 123(Pt 4):401-14. DOI: 10.1017/s0031182001008605. View

20.

Grzybek M, Tolkacz K, Sironen T, Maki S, Alsarraf M, Behnke-Borowczyk J . Zoonotic Viruses in Three Species of Voles from Poland. Animals (Basel). 2020; 10(10). PMC: 7599905. DOI: 10.3390/ani10101820. View