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Transposable Genetic Elements As Agents of Gene Instability and Chromosomal Rearrangements

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Journal Nature
Specialty Science
Date 1977 Jul 14
PMID 339095
Citations 69
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Abstract

Transposable genetic elements in prokaryotes and eukaryotes, when inserted at a given locus, can control expression of the locus and cause large scale rearrangements of adjacent DNA sequences. Striking similarities in genetic behaviour between the two groups of elements have led to the proposal of a molecular model of eukaryotic controlling elements, and to suggestions about the part such elements may play in evolution and differentiation.

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