Coexistence of Hidradenitis Suppurativa and Steatocystoma Multiplex: Is It a New Variant of Hidradenitis Suppurativa?

Overview

Journal J Cutan Med Surg

Publisher Sage Publications

Specialties Dermatology
General Surgery

Date 2021 Apr 28

PMID 33908804

Citations 1

Authors

Joshua Fletcher

Claudia Posso-De Los Rios

Jadranka Jambrosic

Afsaneh Alavi

Affiliations

Soon will be listed here.

Abstract

Hidradenitis suppurativa and steatocystoma multiplex may coexist in the same patient. The overlap of these 2 conditions could be suggestive of an unrecognized defect in follicular proliferation mutual in the pathogenesis of both conditions. Here we present 5 patients with both hidradenitis suppurativa and steatocystoma multiplex. Recognizing the overlap between these 2 conditions is important for accurate diagnosis, management, and identification of potential surgical candidates, as well as future basic science research.

Citing Articles

Steatocystoma Multiplex.

Palaniappan V, Karthikeyan K Indian Dermatol Online J. 2024; 15(1):105-112.

PMID: 38283021 PMC: 10810380. DOI: 10.4103/idoj.idoj_490_23.

References

Santana C, Pereira D, Lisboa A, Leal J, Obadia D, da Silva R . Steatocystoma multiplex suppurativa: case report of a rare condition. An Bras Dermatol. 2017; 91(5 suppl 1):51-53. PMC: 5324992. DOI: 10.1590/abd1806-4841.20164539. View

Covello S, Smith F, Sillevis Smitt J, Paller A, Munro C, Jonkman M . Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2. Br J Dermatol. 1998; 139(3):475-80. DOI: 10.1046/j.1365-2133.1998.02413.x. View

Adams B, Shwayder T . Steatocystoma multiplex suppurativum. Int J Dermatol. 2008; 47(11):1155-6. DOI: 10.1111/j.1365-4632.2008.03698.x. View

Cho S, Chang S, Choi J, Sung K, Moon K, Koh J . Clinical and histologic features of 64 cases of steatocystoma multiplex. J Dermatol. 2002; 29(3):152-6. DOI: 10.1111/j.1346-8138.2002.tb00238.x. View

Bedlow A, Mortimer P . Dowling-Degos disease associated with hidradenitis suppurativa. Clin Exp Dermatol. 1996; 21(4):305-6. DOI: 10.1111/j.1365-2230.1996.tb00103.x. View

Apaydin R, Bilen N, Bayramgurler D, Basdas F, Harova G, Dokmeci S . Steatocystoma multiplex suppurativum: oral isotretinoin treatment combined with cryotherapy. Australas J Dermatol. 2000; 41(2):98-100. DOI: 10.1046/j.1440-0960.2000.00403.x. View

McDonald R, REED W . Natal teeth and steatocystoma multiplex complicated by hidradenitis suppurativa. A new syndrome. Arch Dermatol. 1976; 112(8):1132-4. View

Loo W, Rytina E, Todd P . Hidradenitis suppurativa, Dowling-Degos and multiple epidermal cysts: a new follicular occlusion triad. Clin Exp Dermatol. 2004; 29(6):622-4. DOI: 10.1111/j.1365-2230.2004.01631.x. View

Vural S, Gundogdu M, Kundakci N, Ruzicka T . Familial Mediterranean fever patients with hidradenitis suppurativa. Int J Dermatol. 2017; 56(6):660-663. DOI: 10.1111/ijd.13503. View

10.

Kim Y, Davis M, Schanbacher C, Su W . Dowling-Degos disease (reticulate pigmented anomaly of the flexures): a clinical and histopathologic study of 6 cases. J Am Acad Dermatol. 1999; 40(3):462-7. DOI: 10.1016/s0190-9622(99)70498-6. View

11.

Hollmig T, Menter A . Familial coincidence of hidradenitis suppurativa and steatocystoma multiplex. Clin Exp Dermatol. 2009; 35(4):e151-2. DOI: 10.1111/j.1365-2230.2009.03742.x. View

12.

Pavlovsky M, Sarig O, Eskin-Schwartz M, Malchin N, Bochner R, Mohamad J . A phenotype combining hidradenitis suppurativa with Dowling-Degos disease caused by a founder mutation in PSENEN. Br J Dermatol. 2017; 178(2):502-508. DOI: 10.1111/bjd.16000. View

13.

Scheinfeld N . Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis. Dermatol Online J. 2013; 19(6):18558. View

14.

Tamayo-Sanchez L, Duran-McKinster C, de la Luz Orozco M, Ruiz-Maldonado R . Keratitis, ichthyosis, and deafness (KID syndrome): review of the literature and proposal of a new terminology. Pediatr Dermatol. 1996; 13(2):105-13. DOI: 10.1111/j.1525-1470.1996.tb01414.x. View

15.

Alotaibi L, Alsaif M, Alhumidi A, Turkmani M, Alsaif F . Steatocystoma Multiplex Suppurativa: A Case with Unusual Giant Cysts over the Scalp and Neck. Case Rep Dermatol. 2019; 11(1):71-76. PMC: 6465725. DOI: 10.1159/000498882. View

16.

Zouboulis C, Desai N, Emtestam L, Hunger R, Ioannides D, Juhasz I . European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa. J Eur Acad Dermatol Venereol. 2015; 29(4):619-44. DOI: 10.1111/jdv.12966. View

17.

Garg A, Strunk A, Midura M, Papagermanos V, Pomerantz H . Prevalence of hidradenitis suppurativa among patients with Down syndrome: a population-based cross-sectional analysis. Br J Dermatol. 2017; 178(3):697-703. DOI: 10.1111/bjd.15770. View

18.

McGrath J . Concurrent hidradenitis suppurativa and Dowling-Degos disease taken down a 'Notch'. Br J Dermatol. 2018; 178(2):328. DOI: 10.1111/bjd.16068. View

19.

Gasparic J, Theut Riis P, Jemec G . Recognizing syndromic hidradenitis suppurativa: a review of the literature. J Eur Acad Dermatol Venereol. 2017; 31(11):1809-1816. DOI: 10.1111/jdv.14464. View

20.

Zussino M, Nazzaro G, Moltrasio C, Marzano A . Coexistence of steatocystoma multiplex and hidradenitis suppurativa: Assessment of this unique association by means of ultrasonography and Color Doppler. Skin Res Technol. 2019; 25(6):877-880. DOI: 10.1111/srt.12751. View