The Nuclear Functions of Long Noncoding RNAs Come into Focus

Overview

Journal Noncoding RNA Res

Date 2021 Apr 26

PMID 33898883

Citations 13

Authors

Zhenxing Song

Jiamei Lin

Zhengguo Li

Chuan Huang

Affiliations

Soon will be listed here.

Abstract

Long noncoding RNAs (lncRNAs), defined as untranslated and tightly-regulated transcripts with a length exceeding 200 nt, are common outputs of the eukaryotic genome. It is becoming increasingly apparent that many lncRNAs likely serve as important regulators in a variety of biological processes. In particular, some of them accumulate in the nucleus and function in diverse nuclear events, including chromatin remodeling, transcriptional regulation, RNA processing, DNA damage repair, etc. Here, we unite recent progresses on the functions of nuclear lncRNAs and provide insights into the future research directions of this field.

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