Dietary Carbohydrate Effects on Histological Features of Ileal Mucosa in White Leghorn Chicken

Overview

Journal J Vet Med Sci

Specialty Veterinary Medicine

Date 2021 Apr 22

PMID 33883363

Citations 2

Authors

Md Salahuddin

Kohzy Hiramatsu

Kento Tamura

Kazumi Kita

Affiliations

Soon will be listed here.

Abstract

White Leghorn chickens were divided into the control, low-carbohydrate (CHO), and CHO-free groups to investigate dietary CHO's significance on histological features of chicken ileal mucosa. Paraffin sections of distal ileum from each chicken were stained by periodic acid-Schiff reaction and subjected to morphometrical analysis. Most villi in the control group had a fingerlike shape but those of the experimental groups showed irregular shapes. Villus height, crypt depth and the number of mitotic cells per crypt were significantly lower in the CHO-free group than in the control group. The density of goblet cells also showed a significant decreasing trend with a reduction in dietary CHO level. In conclusion, dietary CHO positively affects the proliferation of epithelial cells in the chicken ileum.

Citing Articles

Digestion Characteristics of Hydrolyzed Infant Formula and Its Effects on the Growth and Development in Mice.

Feng L, Ye W, Zhang K, Qu D, Liu W, Wu M Front Nutr. 2022; 9:912207.

PMID: 35811942 PMC: 9263559. DOI: 10.3389/fnut.2022.912207.

Dietary carbohydrate modifies the density of L cells in the chicken ileum.

Salahuddin M, Hiramatsu K, Nishimoto I, Kita K J Vet Med Sci. 2022; 84(2):265-274.

PMID: 34980756 PMC: 8920715. DOI: 10.1292/jvms.21-0572.

References

Cheled-Shoval S, Amit-Romach E, Barbakov M, Uni Z . The effect of in ovo administration of mannan oligosaccharide on small intestine development during the pre- and posthatch periods in chickens. Poult Sci. 2011; 90(10):2301-10. DOI: 10.3382/ps.2011-01488. View

Guan X, Karpen H, Stephens J, Bukowski J, Niu S, Zhang G . GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Gastroenterology. 2006; 130(1):150-64. DOI: 10.1053/j.gastro.2005.11.005. View

Baurhoo B, Ferket P, Zhao X . Effects of diets containing different concentrations of mannanoligosaccharide or antibiotics on growth performance, intestinal development, cecal and litter microbial populations, and carcass parameters of broilers. Poult Sci. 2009; 88(11):2262-72. DOI: 10.3382/ps.2008-00562. View

Karhunen L, Juvonen K, Huotari A, Purhonen A, Herzig K . Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans. Regul Pept. 2008; 149(1-3):70-8. DOI: 10.1016/j.regpep.2007.10.008. View

Creamer B . VARIATIONS IN SMALL-INTESTINAL VILLOUS SHAPE AND MUCOSAL DYNAMICS. Br Med J. 1964; 2(5421):1371-3. PMC: 1817301. DOI: 10.1136/bmj.2.5421.1371. View

Burrin D, Stoll B, Guan X . Glucagon-like peptide 2 function in domestic animals. Domest Anim Endocrinol. 2003; 24(2):103-22. DOI: 10.1016/s0739-7240(02)00210-2. View

Imondi A, BIRD F . The turnover of intestinal epithelium in the chick. Poult Sci. 1966; 45(1):142-7. DOI: 10.3382/ps.0450142. View

Drucker D . Biologic actions and therapeutic potential of the proglucagon-derived peptides. Nat Clin Pract Endocrinol Metab. 2006; 1(1):22-31. DOI: 10.1038/ncpendmet0017. View

Awad W, Ghareeb K, Abdel-Raheem S, Bohm J . Effects of dietary inclusion of probiotic and synbiotic on growth performance, organ weights, and intestinal histomorphology of broiler chickens. Poult Sci. 2008; 88(1):49-56. DOI: 10.3382/ps.2008-00244. View

10.

Munyaka P, Echeverry H, Yitbarek A, Camelo-Jaimes G, Sharif S, Guenter W . Local and systemic innate immunity in broiler chickens supplemented with yeast-derived carbohydrates. Poult Sci. 2012; 91(9):2164-72. DOI: 10.3382/ps.2012-02306. View

11.

Smirnov A, Sklan D, Uni Z . Mucin dynamics in the chick small intestine are altered by starvation. J Nutr. 2004; 134(4):736-42. DOI: 10.1093/jn/134.4.736. View

12.

Bar-Shira E, Cohen I, Elad O, Friedman A . Role of goblet cells and mucin layer in protecting maternal IgA in precocious birds. Dev Comp Immunol. 2013; 44(1):186-94. DOI: 10.1016/j.dci.2013.12.010. View

13.

Thomsen L, Bach Knudsen K, Hedemann M, Roepstorff A . The effect of dietary carbohydrates and Trichuris suis infection on pig large intestine tissue structure, epithelial cell proliferation and mucin characteristics. Vet Parasitol. 2006; 142(1-2):112-22. DOI: 10.1016/j.vetpar.2006.05.032. View

14.

van Leeuwen P, Mouwen J, Van der Klis J, Verstegen M . Morphology of the small intestinal mucosal surface of broilers in relation to age, diet formulation, small intestinal microflora and performance. Br Poult Sci. 2004; 45(1):41-8. DOI: 10.1080/00071660410001668842. View

15.

Lovshin J, Drucker D . New frontiers in the biology of GLP-2. Regul Pept. 2000; 90(1-3):27-32. DOI: 10.1016/s0167-0115(00)00117-8. View

16.

Sakata T . Stimulatory effect of short-chain fatty acids on epithelial cell proliferation of isolated and denervated jejunal segment of the rat. Scand J Gastroenterol. 1989; 24(7):886-90. DOI: 10.3109/00365528909089230. View

17.

Yamauchi K, Isshiki Y . Scanning electron microscopic observations on the intestinal villi in growing White Leghorn and broiler chickens from 1 to 30 days of age. Br Poult Sci. 1991; 32(1):67-78. DOI: 10.1080/00071669108417328. View

18.

Shang Y, Regassa A, Kim J, Kim W . The effect of dietary fructooligosaccharide supplementation on growth performance, intestinal morphology, and immune responses in broiler chickens challenged with Salmonella Enteritidis lipopolysaccharides. Poult Sci. 2015; 94(12):2887-97. DOI: 10.3382/ps/pev275. View

19.

Adebowale T, Shunshun J, Yao K . The effect of dietary high energy density and carbohydrate energy ratio on digestive enzymes activity, nutrient digestibility, amino acid utilization and intestinal morphology of weaned piglets. J Anim Physiol Anim Nutr (Berl). 2019; 103(5):1492-1502. DOI: 10.1111/jpn.13123. View

20.

Bar Shira E, Friedman A . Innate immune functions of avian intestinal epithelial cells: Response to bacterial stimuli and localization of responding cells in the developing avian digestive tract. PLoS One. 2018; 13(7):e0200393. PMC: 6034880. DOI: 10.1371/journal.pone.0200393. View