The Role of Epigenetics, Particularly DNA Methylation, in the Evolution of Caste in Insect Societies

Overview

Journal Philos Trans R Soc Lond B Biol Sci

Specialty Biology

Date 2021 Apr 19

PMID 33866805

Citations 19

Authors

Benjamin P Oldroyd

Boris Yagound

Affiliations

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Abstract

Eusocial insects can be defined as those that live in colonies and have distinct queens and workers. For most species, queens and workers arise from a common genome, and so caste-specific developmental trajectories must arise from epigenetic processes. In this review, we examine the epigenetic mechanisms that may be involved in the regulation of caste dimorphism. Early work on honeybees suggested that DNA methylation plays a causal role in the divergent development of queen and worker castes. This view has now been challenged by studies that did not find consistent associations between methylation and caste in honeybees and other species. Evidence for the involvement of methylation in modulating behaviour of adult workers is also inconsistent. Thus, the functional significance of DNA methylation in social insects remains equivocal. This article is part of the theme issue 'How does epigenetics influence the course of evolution?'

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