Developments and Opportunities in Continuous Biopharmaceutical Manufacturing

Overview

Journal MAbs

Specialty Allergy & Immunology

Date 2021 Apr 12

PMID 33843449

Citations 13

Authors

Ohnmar Khanal

Abraham M Lenhoff

Affiliations

Soon will be listed here.

Abstract

Today's biologics manufacturing practices incur high costs to the drug makers, which can contribute to high prices for patients. Timely investment in the development and implementation of continuous biomanufacturing can increase the production of consistent-quality drugs at a lower cost and a faster pace, to meet growing demand. Efficient use of equipment, manufacturing footprint, and labor also offer the potential to improve drug accessibility. Although technological efforts enabling continuous biomanufacturing have commenced, challenges remain in the integration, monitoring, and control of traditionally segmented unit operations. Here, we discuss recent developments supporting the implementation of continuous biomanufacturing, along with their benefits.

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