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Biodegradable Materials for Sustainable Health Monitoring Devices

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Date 2021 Apr 12
PMID 33842859
Citations 31
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Abstract

The recent advent of biodegradable materials has offered huge opportunity to transform healthcare technologies by enabling sensors that degrade naturally after use. The implantable electronic systems made from such materials eliminate the need for extraction or reoperation, minimize chronic inflammatory responses, and hence offer attractive propositions for future biomedical technology. The eco-friendly sensor systems developed from degradable materials could also help mitigate some of the major environmental issues by reducing the volume of electronic or medical waste produced and, in turn, the carbon footprint. With this background, herein we present a comprehensive overview of the structural and functional biodegradable materials that have been used for various biodegradable or bioresorbable electronic devices. The discussion focuses on the dissolution rates and degradation mechanisms of materials such as natural and synthetic polymers, organic or inorganic semiconductors, and hydrolyzable metals. The recent trend and examples of biodegradable or bioresorbable materials-based sensors for body monitoring, diagnostic, and medical therapeutic applications are also presented. Lastly, key technological challenges are discussed for clinical application of biodegradable sensors, particularly for implantable devices with wireless data and power transfer. Promising perspectives for the advancement of future generation of biodegradable sensor systems are also presented.

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References
1.
Mostert A, Powell B, Pratt F, Hanson G, Sarna T, Gentle I . Role of semiconductivity and ion transport in the electrical conduction of melanin. Proc Natl Acad Sci U S A. 2012; 109(23):8943-7. PMC: 3384144. DOI: 10.1073/pnas.1119948109. View

2.
Smith B, Tang Z, Johnson M, Pourmehdi S, Gazdik M, Buckett J . An externally powered, multichannel, implantable stimulator-telemeter for control of paralyzed muscle. IEEE Trans Biomed Eng. 1998; 45(4):463-75. DOI: 10.1109/10.664202. View

3.
Bai W, Shin J, Fu R, Kandela I, Lu D, Ni X . Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity. Nat Biomed Eng. 2019; 3(8):644-654. DOI: 10.1038/s41551-019-0435-y. View

4.
Li W, Liu Q, Zhang Y, Li C, He Z, Choy W . Biodegradable Materials and Green Processing for Green Electronics. Adv Mater. 2020; 32(33):e2001591. DOI: 10.1002/adma.202001591. View

5.
Liao C, Zhang M, Yao M, Hua T, Li L, Yan F . Flexible Organic Electronics in Biology: Materials and Devices. Adv Mater. 2014; 27(46):7493-527. DOI: 10.1002/adma.201402625. View