» Articles » PMID: 3382564

The Dobutamine Stress Test As an Alternative to Exercise Testing After Acute Myocardial Infarction

Overview
Journal Br Heart J
Date 1988 May 1
PMID 3382564
Citations 14
Authors
Affiliations
Soon will be listed here.
Abstract

Three weeks after myocardial infarction in 50 patients the effect of the infusion of a graded dose of dobutamine was compared with that of symptom limited treadmill exercise testing. The following variables were measured: blood pressure, heart rate, ST segment changes, Doppler aortic blood flow, and cross sectional echocardiographic dimensions. The heart rate and double product increased more during exercise than during dobutamine infusion, while maximum acceleration in the ascending aorta increased more during dobutamine infusion than during exercise. Significant ST depression was recorded in 22 patients during exercise and in 24 during dobutamine infusion; the concordance between the two tests was 88%. In all cases in which ST segment depression occurred in both tests the site of ST depression was the same. Dobutamine stress testing is an alternative to exercise testing in patients after myocardial infarction.

Citing Articles

Tipping the scales of understanding: An engineering approach to design and implement whole-body cardiac electrophysiology experimental models.

Zenger B, Bergquist J, Busatto A, Good W, Rupp L, Sharma V Front Physiol. 2023; 14:1100471.

PMID: 36744034 PMC: 9893785. DOI: 10.3389/fphys.2023.1100471.


Pharmacological and simulated exercise cardiac stress tests produce different ischemic signatures in high-resolution experimental mapping studies.

Zenger B, Good W, Bergquist J, Rupp L, Perez M, Stoddard G J Electrocardiol. 2021; 68:56-64.

PMID: 34339897 PMC: 8490320. DOI: 10.1016/j.jelectrocard.2021.07.009.


Novel experimental model for studying the spatiotemporal electrical signature of acute myocardial ischemia: a translational platform.

Zenger B, Good W, Bergquist J, Burton B, Tate J, Berkenbile L Physiol Meas. 2019; 41(1):015002.

PMID: 31860892 PMC: 8056277. DOI: 10.1088/1361-6579/ab64b9.


Dobutamine stress echocardiography as a prognostic tool for future cardiac events.

Soofi M, Khan S Ann Saudi Med. 2008; 28(5):371-3.

PMID: 18779638 PMC: 6074494. DOI: 10.5144/0256-4947.2008.371.


Stress echocardiography in the diagnosis of coronary artery disease.

Mazur W, Nagueh S Curr Atheroscler Rep. 2001; 3(2):109-16.

PMID: 11177654 DOI: 10.1007/s11883-001-0046-3.


References
1.
Corbett J, Dehmer G, Lewis S, Woodward W, Henderson E, Parkey R . The prognostic value of submaximal exercise testing with radionuclide ventriculography before hospital discharge in patients with recent myocardial infarction. Circulation. 1981; 64(3):535-44. DOI: 10.1161/01.cir.64.3.535. View

2.
Manca C, Bianchi G, Effendy F, Bolognesi R, Cucchini F, VISIOLI O . Comparison of five different stress testing methods in the ECG diagnosis of coronary artery disease. Correlation with coronary arteriography. Cardiology. 1979; 64(5):325-32. DOI: 10.1159/000170630. View

3.
Josephson M, Brown B, Hecht H, Hopkins J, Pierce C, Petersen R . Noninvasive detection and localization of coronary stenoses in patients: comparison of resting dipyridamole and exercise thallium-201 myocardial perfusion imaging. Am Heart J. 1982; 103(6):1008-18. DOI: 10.1016/0002-8703(82)90564-6. View

4.
NICOD P, Corbett J, Firth B, Lewis S, Rude R, Huxley R . Prognostic value of resting and submaximal exercise radionuclide ventriculography after acute myocardial infarction in high-risk patients with single and multivessel disease. Am J Cardiol. 1983; 52(1):30-6. DOI: 10.1016/0002-9149(83)90064-4. View

5.
Mason J, Palac R, Freeman M, Virupannavar S, Loeb H, Kaplan E . Thallium scintigraphy during dobutamine infusion: nonexercise-dependent screening test for coronary disease. Am Heart J. 1984; 107(3):481-5. DOI: 10.1016/0002-8703(84)90089-9. View