Recent Advances in Understanding and Treating Scabies
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Scabies is an infestation of the skin caused by the mite In 2017, scabies was recognised by the World Health Organisation as a disease of public importance and was consequently added to the list of neglected tropical diseases. An estimated 200 million people currently have scabies worldwide. Scabies is endemic in many developing countries, with the highest prevalence being in hot, humid climates such as the Pacific and Latin American regions. Scabies causes a host immune response which is intensely itchy. Scratching of the lesions can lead to secondary bacterial infections of the skin, such as impetigo, most commonly caused by or . This can have fatal consequences, such as septicaemia, glomerulonephritis, and rheumatic heart disease. Advances over the past 5 years indicate that mass drug administration is an effective strategy to treat scabies. This review will outline advances in the mite biology, epidemiological understanding, diagnosis, and treatment of scabies.
Li J, Liu Z, Xia X PLoS Negl Trop Dis. 2024; 18(12):e0012775.
PMID: 39724068 PMC: 11709319. DOI: 10.1371/journal.pntd.0012775.
Fernando D, Mounsey K, Bernigaud C, Surve N, Estrada Chavez G, Hay R Nat Rev Dis Primers. 2024; 10(1):74.
PMID: 39362885 DOI: 10.1038/s41572-024-00552-8.
Zewude B, Tadele G, Davey G PLoS Negl Trop Dis. 2024; 18(9):e0012475.
PMID: 39241002 PMC: 11410222. DOI: 10.1371/journal.pntd.0012475.
Brookes V, Henning C, Worthing K, Degeling C PLoS Negl Trop Dis. 2024; 18(5):e0012115.
PMID: 38696362 PMC: 11065235. DOI: 10.1371/journal.pntd.0012115.
Study of the Use of Permethrin 5% Cream in Galicia (Spain) between 2018 and 2021.
Vazquez-Prieto S, Vaamonde A, Paniagua E Infect Dis Rep. 2023; 15(2):222-230.
PMID: 37102983 PMC: 10138315. DOI: 10.3390/idr15020023.