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Recent Advances in Understanding and Treating Scabies

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Journal Fac Rev
Date 2021 Apr 5
PMID 33817697
Citations 7
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Abstract

Scabies is an infestation of the skin caused by the mite In 2017, scabies was recognised by the World Health Organisation as a disease of public importance and was consequently added to the list of neglected tropical diseases. An estimated 200 million people currently have scabies worldwide. Scabies is endemic in many developing countries, with the highest prevalence being in hot, humid climates such as the Pacific and Latin American regions. Scabies causes a host immune response which is intensely itchy. Scratching of the lesions can lead to secondary bacterial infections of the skin, such as impetigo, most commonly caused by or . This can have fatal consequences, such as septicaemia, glomerulonephritis, and rheumatic heart disease. Advances over the past 5 years indicate that mass drug administration is an effective strategy to treat scabies. This review will outline advances in the mite biology, epidemiological understanding, diagnosis, and treatment of scabies.

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References
1.
Romani L, Marks M, Sokana O, Nasi T, Kamoriki B, Wand H . Feasibility and safety of mass drug coadministration with azithromycin and ivermectin for the control of neglected tropical diseases: a single-arm intervention trial. Lancet Glob Health. 2018; 6(10):e1132-e1138. PMC: 6139784. DOI: 10.1016/S2214-109X(18)30397-8. View

2.
Mounsey K, Bernigaud C, Chosidow O, McCarthy J . Prospects for Moxidectin as a New Oral Treatment for Human Scabies. PLoS Negl Trop Dis. 2016; 10(3):e0004389. PMC: 4795782. DOI: 10.1371/journal.pntd.0004389. View

3.
Romani L, Steer A, Whitfeld M, Kaldor J . Prevalence of scabies and impetigo worldwide: a systematic review. Lancet Infect Dis. 2015; 15(8):960-7. DOI: 10.1016/S1473-3099(15)00132-2. View

4.
Tjioe M, Vissers W . Scabies outbreaks in nursing homes for the elderly: recognition, treatment options and control of reinfestation. Drugs Aging. 2008; 25(4):299-306. DOI: 10.2165/00002512-200825040-00003. View

5.
Parks T, Smeesters P, Steer A . Streptococcal skin infection and rheumatic heart disease. Curr Opin Infect Dis. 2012; 25(2):145-53. DOI: 10.1097/QCO.0b013e3283511d27. View