COVID-19 and Pulmonary Coinfection-The First Case Confirmed Through Autopsy

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2021 Apr 3

PMID 33804963

Citations 19

Authors

Ionut Isaia Jeican

Patricia Inisca

Dan Gheban

Flaviu Tabaran

Maria Aluas

Veronica Trombitas

Victor Cristea

Carmen Crivii

Lia Monica Junie

Silviu Albu

Affiliations

Soon will be listed here.

Abstract

: Establishing the diagnosis of COVID-19 and pulmonary coinfection is difficult due to clinical and radiological similarities that exist between the two disorders. For the moment, fungal coinfections are underestimated in COVID-19 patients. : We report the case of a 52-year-old male patient, who presented to the emergency department for severe dyspnea and died 17 h later. The RT-PCR test performed at his admission was negative for SARS-CoV-2. Retesting of lung fragments collected during autopsy revealed a positive result for SARS-CoV-2. Histopathological examination showed preexisting lesions, due to comorbidities, as well as recent lesions: massive lung thromboses, alveolar exudate rich in foam cells, suprapleural and intra-alveolar cystic forms, and bilateral adrenal hemorrhage. : COVID-19 and coinfection should be considered, particularly in critically ill patients, and we recommend the systematic search for in respiratory samples.

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