Medical Versus Surgical Treatment for the Management of Diabetic Foot Osteomyelitis: A Systematic Review

Overview

Journal J Clin Med

Specialty General Medicine

Date 2021 Apr 3

PMID 33802685

Citations 10

Authors

Aroa Tardaguila-Garcia

Irene Sanz-Corbalan

Josep M Garcia-Alamino

Raju Ahluwalia

Luigi Uccioli

Jose Luis Lazaro-Martinez

Affiliations

Soon will be listed here.

Abstract

A systematic review and quality assessment was performed to assess the management of diabetic foot osteomyelitis by medical or surgical treatment. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was used. All selected studies were evaluated using the Cochrane Risk of Bias Tool to assess the risk of bias for randomized controlled trials. The literature was revised using PubMed (Medline) and Embase (Elsevier) up to September 2020 to identify clinical trials assessing medical or surgical treatment to manage diabetic foot osteomyelitis. A total of six clinical trials that met our inclusion criteria, with a total of 308 participants. Healing rate, complete closure of the wound, and type of complications were the outcomes evaluated. Risk of bias assessment showed that only two of the six clinical trials included in the systematic review had a low risk of bias. Based on our findings, we believe that the management of diabetic foot osteomyelitis remains challenging. There are few high-quality clinical trials that both stratify clinical presentations and compare these treatments. We conclude that the available evidence is insufficient to identify the best option to cure diabetic foot osteomyelitis.

Citing Articles

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Analysis of the Influence of Diabetic Nephropathy in Patients with Diabetic Foot Osteomyelitis.

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Bacterial Diversity and Antibiotic Resistance in Patients with Diabetic Foot Osteomyelitis.

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