Development of a Digital Breast Phantom for Photoacoustic Computed Tomography

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2021 Apr 2

PMID 33796361

Citations 9

Authors

Youwei Bao

Handi Deng

Xuanhao Wang

Hongzhi Zuo

Cheng Ma

Affiliations

Soon will be listed here.

Abstract

Photoacoustic (PA) imaging provides morphological and functional information about angiogenesis and thus is potentially suitable for breast cancer diagnosis. However, the development of PA breast imaging has been hindered by inadequate patients and a lack of ground truth images. Here, we report a digital breast phantom with realistic acoustic and optical properties, with which a digital PA-ultrasound imaging pipeline is developed to create a diverse pool of virtual patients with three types of masses: ductal carcinoma in situ, invasive breast cancer, and fibroadenoma. The experimental results demonstrate that our model is realistic, flexible, and can be potentially useful for accelerating the development of PA breast imaging technology.

Citing Articles

Challenges and advances in two-dimensional photoacoustic computed tomography: a review.

Zhang S, Miao J, Li L J Biomed Opt. 2024; 29(7):070901.

PMID: 39006312 PMC: 11245175. DOI: 10.1117/1.JBO.29.7.070901.

Mitigating Under-Sampling Artifacts in 3D Photoacoustic Imaging Using Res-UNet Based on Digital Breast Phantom.

Huo H, Deng H, Gao J, Duan H, Ma C Sensors (Basel). 2023; 23(15).

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Stochastic three-dimensional numerical phantoms to enable computational studies in quantitative optoacoustic computed tomography of breast cancer.

Park S, Villa U, Li F, Cam R, Oraevsky A, Anastasio M J Biomed Opt. 2023; 28(6):066002.

PMID: 37347003 PMC: 10281048. DOI: 10.1117/1.JBO.28.6.066002.

Photoacoustic digital brain and deep-learning-assisted image reconstruction.

Zhang F, Zhang J, Shen Y, Gao Z, Yang C, Liang M Photoacoustics. 2023; 31:100517.

PMID: 37292518 PMC: 10244697. DOI: 10.1016/j.pacs.2023.100517.

Optical Resolution Photoacoustic Microscopy Imaging in the Detection of Early Oral Cancer under Image Reconstruction Algorithm.

Zhang L, Wang X Comput Math Methods Med. 2022; 2022:6077748.

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