Genome-wide Association Study of Fleece Traits in Inner Mongolia Cashmere Goats

Overview

Journal Anim Genet

Specialties Biology
Genetics

Date 2021 Mar 29

PMID 33778967

Citations 17

Authors

F H Wang

L Zhang

G Gong

X C Yan

L T Zhang

F T Zhang

H F Liu

Q Lv

Z Y Wang

R J Wang

Y J Zhang

Z X Wang

Z H Liu

L B He

R Su

Y H Zhao

J Q Li

Affiliations

Soon will be listed here.

Abstract

Inner Mongolia Cashmere goat is a well-known local cashmere goat breed in China. It is famous for excellent fleece quality and a significant advantage in cashmere yield compared to other cashmere goat breeds. In this study, a genome-wide association study was used to investigate fiber length, fiber diameter, and cashmere yield of 192 Inner Mongolia Cashmere goats using the Illumina GoatSNP52K Beadchip panel. We discovered that four single nucleotide polymorphisms (SNPs) reached genome-wide significance levels. These SNPs were located in some genes, e.g. FGF12, SEMA3D, EVPL, and SOX5, possibly related to fleece traits in Inner Mongolia Cashmere goat. Gene ontology enrichment analysis revealed that these genes were enriched in several biological pathways that were involved in hair follicle development in cashmere goats. In summary, the identified significant SNPs and genes provide useful information to explore genetic mechanisms underlying the variation in fleece traits and genomic selection of Chinese cashmere goat.

Citing Articles

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Combined Genome-Wide Association Study and Haplotype Analysis Identifies Candidate Genes Affecting Growth Traits of Inner Mongolian Cashmere Goats.

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