Hereditary Persistence of Fetal Hemoglobin

Overview

Journal Asian J Transfus Sci

Specialty Hematology

Date 2021 Mar 26

PMID 33767547

Citations 6

Authors

Dharmesh Chandra Sharma

Sachin Singhal

Poonam Woike

Sunita Rai

Mahesh Yadav

Rajesh Gaur

Affiliations

Soon will be listed here.

Abstract

Hereditary persistence of fetal hemoglobin (HPFH) is a benign condition in which significant fetal hemoglobin production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced. The percentage of incorrect expression might be as low as 10%-15% or as high as 100% of the total hemoglobin, usually higher in homozygotes than in heterozygotes. The present case is a typical example of homozygous HPFH.

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