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SARS-CoV-2 Is Present in Peritoneal Fluid in COVID-19 Patients

Overview
Journal Ann Surg
Specialty General Surgery
Date 2021 Mar 24
PMID 33759843
Citations 102
Authors
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Abstract

Background: The excretion pathomechanisms of SARS-CoV-2 are actually unknown. No certain data exist about viral load in the different body compartments and fluids during the different disease phases.

Material And Methods: Specific real-time reverse transcriptase-polymerase chain reaction targeting 3 SARS-CoV-e genes were used to detect the presence of the virus.

Results: SARS-CoV-2 was detected in peritoneal fluid at a higher concentration than in respiratory tract.

Conclusion: Detection of SARS-CoV-2 in peritoneal fluid has never been reported. The present article represents the very first positive result describing the presence of the virus in peritoneal fluid during an emergency surgical procedure in a COVID-19 sick patient. This article thus represents a warning for increasing the level of awareness and protection for surgeon especially in emergency surgical setting.

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References
1.
Corman V, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu D . Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020; 25(3). PMC: 6988269. DOI: 10.2807/1560-7917.ES.2020.25.3.2000045. View

2.
Chen X, Zhao B, Qu Y, Chen Y, Xiong J, Feng Y . Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019. Clin Infect Dis. 2020; 71(8):1937-1942. PMC: 7184354. DOI: 10.1093/cid/ciaa449. View

3.
Mallick R, Odejinmi F, Clark T . Covid 19 pandemic and gynaecological laparoscopic surgery: knowns and unknowns. Facts Views Vis Obgyn. 2020; 12(1):3-7. PMC: 7117791. View

4.
Coccolini F, Perrone G, Chiarugi M, DI Marzo F, Ansaloni L, Scandroglio I . Surgery in COVID-19 patients: operational directives. World J Emerg Surg. 2020; 15(1):25. PMC: 7137852. DOI: 10.1186/s13017-020-00307-2. View

5.
Coccolini F, Sartelli M, Kluger Y, Pikoulis E, Karamagioli E, Moore E . COVID-19 the showdown for mass casualty preparedness and management: the Cassandra Syndrome. World J Emerg Surg. 2020; 15(1):26. PMC: 7145275. DOI: 10.1186/s13017-020-00304-5. View