Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis

Overview

Journal Intern Med

Specialty General Medicine

Date 2021 Mar 22

PMID 33746170

Authors

Ayaka Kume

Daisuke Kashiwakuma

Ai Kubodera

Kiyohito Hayashi

Ryo Shimizu

Yoshio Suzuki

Hiroaki Tanaka

Affiliations

Soon will be listed here.

Abstract

Lymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. Because MBL is difficult to diagnose, cases like ours may not be rare. These findings will facilitate our understanding of the mechanism underlying lymphoproliferative diseases and autoimmune diseases.

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