UV-C Irradiation is Highly Effective in Inactivating SARS-CoV-2 Replication

Overview

Journal Sci Rep

Specialty Science

Date 2021 Mar 19

PMID 33737536

Citations 127

Authors

Mara Biasin

Andrea Bianco

Giovanni Pareschi

Adalberto Cavalleri

Claudia Cavatorta

Claudio Fenizia

Paola Galli

Luigi Lessio

Manuela Lualdi

Enrico Tombetti

Alessandro Ambrosi

Edoardo Maria Alberto Redaelli

Irma Saulle

Daria Trabattoni

Alessio Zanutta

Mario Clerici

Affiliations

Soon will be listed here.

Abstract

The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.

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