Analysis of Chemical Compounds and Toxicological Evaluation of Leaves Tea

Overview

Journal Food Sci Biotechnol

Specialty Biotechnology

Date 2021 Mar 18

PMID 33732521

Citations 3

Authors

Da-Hong Wang

Meng-Yang Wang

Wen-Hao Shen

Jiang-Feng Yuan

Affiliations

Soon will be listed here.

Abstract

To determine the compositions of leaves tea (FSLT) and its safety, the chemical compounds were analysed with some methods, and the toxicity was evaluated in Kunming mice and Wistar rats. The results showed that FSLT contained rich flavonoid, lignans, triperpene acids, amino acids, and mineral elements. In the acute toxicity study, none of the mice died, and no obvious poisoning symptoms were observed after 14 days in mice at the dose of 15 mg/g·body weight (bw) FSLT; in the sub-chronic toxicity, no abnormal or dead rat was found at the dose of 1, 3, and 10 mg/g·bw during 90 days feeding administration; there was no significant difference in bw and food consumption; no significant differences were found in each hematology and serum biochemistry parameter and organ/body weight ratio comparing with the control experimental group. The results revealed that the FSLT has low or no toxicity via oral administration. Therefore, FSLT is very suitable and safe to be used as a new resource food.

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