» Articles » PMID: 33732085

Adverse Effects of Atrazine on Blood Parameters, Biochemical Profile and Genotoxicity of Snow Trout ()

Overview
Specialty Biology
Date 2021 Mar 18
PMID 33732085
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

This study was conducted to evaluate the adverse effects of atrazine on hematology, biochemistry and genotoxicity of snow trout (). Almost all treated groups presented considerably ( < 0.05) lesser values of hematocrit, hemoglobin, WBC, RBC, MCH, MCHC, monocytes and lymphocytes while significantly higher values of HCT and platelets are observed. A Significant decrease is observed in sodium, calcium, potassium, phosphorous, triglycerides, creatinine, urea, and total protein contents whereas, a significant increase is observed in cholesterol and glucose level. Significant ( < 0.05) alterations are observed in enzyme activities of all treated groups. DNA damage was observed at the concentrations (2-4 ppm). Results showed that Comet assay is reliable for evaluating the toxicity and is helpful in environmental monitoring programs.

Citing Articles

Hepatotoxicity in Carp () Exposed to Perfluorooctane Sulfonate (PFOS): Integrative Histopathology and Transcriptomics Analysis.

Tang L, Hao G, Zhou D, Fan Y, Wei Z, Li D Animals (Basel). 2025; 15(4).

PMID: 40003090 PMC: 11851982. DOI: 10.3390/ani15040610.


Atrazine Toxicity: The Possible Role of Natural Products for Effective Treatment.

Das S, Sakr H, Al-Huseini I, Jetti R, Al-Qasmi S, Sugavasi R Plants (Basel). 2023; 12(12).

PMID: 37375903 PMC: 10301673. DOI: 10.3390/plants12122278.


Zinc Oxide Nanoparticles and Vitamin C Ameliorate Atrazine-Induced Hepatic Apoptosis in Rat via CYP450s/ROS Pathway and Immunomodulation.

Mohammed E, Safwat G, Bahnasawy E, Abdel-Razik A, Mohamed D Biol Trace Elem Res. 2023; 201(11):5257-5271.

PMID: 36790584 PMC: 10509061. DOI: 10.1007/s12011-023-03587-2.


Toxicological impact of Zinc Nano Particles on tilapia fish ().

Khan G, Akhtar N, Khan M, Ullah Z, Tabassum S, Tedesse Z Saudi J Biol Sci. 2022; 29(2):1221-1226.

PMID: 35197788 PMC: 8847941. DOI: 10.1016/j.sjbs.2021.09.044.


Blood Performance: A New Formula for Fish Growth and Health.

Esmaeili M Biology (Basel). 2021; 10(12).

PMID: 34943151 PMC: 8698978. DOI: 10.3390/biology10121236.


References
1.
Nwani C, Lakra W, Nagpure N, Kumar R, Kushwaha B, Srivastava S . Toxicity of the herbicide atrazine: effects on lipid peroxidation and activities of antioxidant enzymes in the freshwater fish Channa punctatus (Bloch). Int J Environ Res Public Health. 2010; 7(8):3298-312. PMC: 2954582. DOI: 10.3390/ijerph7083298. View

2.
Solomon K, Carr J, du Preez L, Giesy J, Kendall R, Smith E . Effects of atrazine on fish, amphibians, and aquatic reptiles: a critical review. Crit Rev Toxicol. 2008; 38(9):721-72. DOI: 10.1080/10408440802116496. View

3.
Fu Y, Li M, Liu C, Qu J, Zhu W, Xing H . Effect of atrazine and chlorpyrifos exposure on cytochrome P450 contents and enzyme activities in common carp gills. Ecotoxicol Environ Saf. 2013; 94:28-36. DOI: 10.1016/j.ecoenv.2013.04.018. View

4.
Plhalova L, Blahova J, Mikulikova I, Stepanova S, Dolezelova P, Praskoval E . Effects of subchronic exposure to atrazine on zebrafish (Danio rerio). Pol J Vet Sci. 2012; 15(3):417-23. DOI: 10.2478/v10181-012-0065-8. View

5.
Tillitt D, Papoulias D, Whyte J, Richter C . Atrazine reduces reproduction in fathead minnow (Pimephales promelas). Aquat Toxicol. 2010; 99(2):149-59. DOI: 10.1016/j.aquatox.2010.04.011. View