Complex 3D Bioprinting Methods

Overview

Journal APL Bioeng

Date 2021 Mar 17

PMID 33728391

Citations 27

Authors

Shen Ji

Murat Guvendiren

Affiliations

Soon will be listed here.

Abstract

3D bioprinting technology is evolving in complexity to enable human-scale, high-resolution, and multi-cellular constructs to better mimic the native tissue microenvironment. The ultimate goal is to achieve necessary complexity in the bioprinting process to biomanufacture fully-functional tissues and organs to address organ shortage and lack of patient-specific disease models. In this Review, we presented an in-depth overview of complex 3D bioprinting approaches including evolution of complex bioprinting, from simple gel-casting approach to multi-material bioprinting to omnidirectional bioprinting approaches, and emerging bioprinting approaches, including 4D bioprinting and bioprinting technologies.

Citing Articles

Microgel-based bioink for extrusion-based 3D bioprinting and its applications in tissue engineering.

Iyer K, Bao L, Zhai J, Jayachandran A, Luwor R, Li J Bioact Mater. 2025; 48:273-293.

PMID: 40060146 PMC: 11889356. DOI: 10.1016/j.bioactmat.2025.02.003.

Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.

Rasouli R, Sweeney C, Frampton J Biomed Mater Devices. 2025; 3(1):108-126.

PMID: 40028238 PMC: 11868245. DOI: 10.1007/s44174-024-00171-7.

Remote-Controlled Gene Delivery in Coaxial 3D-Bioprinted Constructs using Ultrasound-Responsive Bioinks.

Lowrey M, Day H, Schilling K, Huynh K, Franca C, Schutt C Cell Mol Bioeng. 2024; 17(5):401-421.

PMID: 39513003 PMC: 11538209. DOI: 10.1007/s12195-024-00818-x.

Regenerative rehabilitation: a novel multidisciplinary field to maximize patient outcomes.

Deng C, Aldali F, Luo H, Chen H Med Rev (2021). 2024; 4(5):413-434.

PMID: 39444794 PMC: 11495474. DOI: 10.1515/mr-2023-0060.

Photocuring 3D printing technology as an advanced tool for promoting angiogenesis in hypoxia-related diseases.

Lee S, Phuc H, Um S, Mongrain R, Yoon J, Bhang S J Tissue Eng. 2024; 15:20417314241282476.

PMID: 39345255 PMC: 11437565. DOI: 10.1177/20417314241282476.

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