B Cells in Idiopathic Pulmonary Fibrosis: Targeting Immune Cells with Antifibrotic Agents

Overview

Journal Am J Respir Cell Mol Biol

Specialties Cell Biology
Molecular Biology

Date 2021 Mar 16

PMID 33725473

Citations 5

Authors

Jesse Roman

Hirofumi Chiba

Affiliations

Soon will be listed here.

Citing Articles

Pulmonary fibrosis: pathogenesis and therapeutic strategies.

Wang J, Li K, Hao D, Li X, Zhu Y, Yu H MedComm (2020). 2024; 5(10):e744.

PMID: 39314887 PMC: 11417429. DOI: 10.1002/mco2.744.

Cellular and Molecular Genetic Mechanisms of Lung Fibrosis Development and the Role of Vitamin D: A Review.

Enzel D, Kriventsov M, Sataieva T, Malygina V Int J Mol Sci. 2024; 25(16).

PMID: 39201632 PMC: 11355055. DOI: 10.3390/ijms25168946.

Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis.

Sun Z, Lou Y, Hu X, Song F, Zheng X, Hu Y BMC Pulm Med. 2023; 23(1):149.

PMID: 37118713 PMC: 10148423. DOI: 10.1186/s12890-023-02424-5.

Potential of resveratrol in the treatment of interstitial lung disease.

Huo R, Huang X, Yang Y, Yang Y, Lin J Front Pharmacol. 2023; 14:1139460.

PMID: 37089962 PMC: 10117935. DOI: 10.3389/fphar.2023.1139460.

Immunophenotyping of Acute Inflammatory Exacerbations of Lung Injury Driven by Mutant Surfactant Protein-C: A Role for Inflammatory Eosinophils.

Nguyen J, Armstrong B, Cowman S, Tomer Y, Veerabhadraiah S, Beers M Front Pharmacol. 2022; 13:875887.

PMID: 35571100 PMC: 9094740. DOI: 10.3389/fphar.2022.875887.

References

McDonough J, Ahangari F, Li Q, Jain S, Verleden S, Herazo-Maya J . Transcriptional regulatory model of fibrosis progression in the human lung. JCI Insight. 2019; 4(22). PMC: 6948862. DOI: 10.1172/jci.insight.131597. View

Mathai S, Danoff S . Management of interstitial lung disease associated with connective tissue disease. BMJ. 2016; 352:h6819. PMC: 6887350. DOI: 10.1136/bmj.h6819. View

Ali M, Dasari H, Van Keulen V, Carmona E . Canonical Stimulation of the NLRP3 Inflammasome by Fungal Antigens Links Innate and Adaptive B-Lymphocyte Responses by Modulating IL-1β and IgM Production. Front Immunol. 2017; 8:1504. PMC: 5684107. DOI: 10.3389/fimmu.2017.01504. View

Ali M, Dasari H, Van Keulen V, Cornec D, Vasmatzis G, Peikert T . Microbial Antigens Stimulate Metalloprotease-7 Secretion in Human B-Lymphocytes Using mTOR-Dependent and Independent Pathways. Sci Rep. 2017; 7(1):3869. PMC: 5478602. DOI: 10.1038/s41598-017-04199-2. View

Lederer D, Martinez F . Idiopathic Pulmonary Fibrosis. N Engl J Med. 2018; 378(19):1811-1823. DOI: 10.1056/NEJMra1705751. View

Somogyi V, Chaudhuri N, Torrisi S, Kahn N, Muller V, Kreuter M . The therapy of idiopathic pulmonary fibrosis: what is next?. Eur Respir Rev. 2019; 28(153). PMC: 9488691. DOI: 10.1183/16000617.0021-2019. View

Heukels P, van Hulst J, van Nimwegen M, Boorsma C, Melgert B, von der Thusen J . Enhanced Bruton's tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis. Respir Res. 2019; 20(1):232. PMC: 6814043. DOI: 10.1186/s12931-019-1195-7. View

Hewlett J, Kropski J, Blackwell T . Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targets. Matrix Biol. 2018; 71-72:112-127. PMC: 6146058. DOI: 10.1016/j.matbio.2018.03.021. View

Libby D, Gibofsky A, Fotino M, Waters S, Smith J . Immunogenetic and clinical findings in idiopathic pulmonary fibrosis. Association with the B-cell alloantigen HLA-DR2. Am Rev Respir Dis. 1983; 127(5):618-22. DOI: 10.1164/arrd.1983.127.5.618. View

10.

Vittal R, Mickler E, Fisher A, Zhang C, Rothhaar K, Gu H . Type V collagen induced tolerance suppresses collagen deposition, TGF-β and associated transcripts in pulmonary fibrosis. PLoS One. 2013; 8(10):e76451. PMC: 3804565. DOI: 10.1371/journal.pone.0076451. View

11.

Asai Y, Chiba H, Nishikiori H, Kamekura R, Yabe H, Kondo S . Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis. Respir Res. 2019; 20(1):244. PMC: 6836348. DOI: 10.1186/s12931-019-1216-6. View

12.

Cooper M . The early history of B cells. Nat Rev Immunol. 2015; 15(3):191-7. DOI: 10.1038/nri3801. View

13.

Xue J, Kass D, Bon J, Vuga L, Tan J, Csizmadia E . Plasma B lymphocyte stimulator and B cell differentiation in idiopathic pulmonary fibrosis patients. J Immunol. 2013; 191(5):2089-95. PMC: 3804013. DOI: 10.4049/jimmunol.1203476. View

14.

Noth I, Zhang Y, Ma S, Flores C, Barber M, Huang Y . Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. Lancet Respir Med. 2014; 1(4):309-317. PMC: 3894577. DOI: 10.1016/S2213-2600(13)70045-6. View

15.

Donahoe M, Valentine V, Chien N, Gibson K, Raval J, Saul M . Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis. PLoS One. 2015; 10(6):e0127771. PMC: 4470587. DOI: 10.1371/journal.pone.0127771. View

16.

Salisbury M, Han M, Dickson R, Molyneaux P . Microbiome in interstitial lung disease: from pathogenesis to treatment target. Curr Opin Pulm Med. 2017; 23(5):404-410. PMC: 5638128. DOI: 10.1097/MCP.0000000000000399. View

17.

Hoyne G, Elliott H, Mutsaers S, Prele C . Idiopathic pulmonary fibrosis and a role for autoimmunity. Immunol Cell Biol. 2017; 95(7):577-583. DOI: 10.1038/icb.2017.22. View

18.

Ali M, Egan A, Shaughnessy G, Anderson D, Kottom T, Dasari H . Antifibrotics Modify B-Cell-induced Fibroblast Migration and Activation in Patients with Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2021; 64(6):722-733. PMC: 8456878. DOI: 10.1165/rcmb.2020-0387OC. View