Biocide-Induced Emergence of Antibiotic Resistance in

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2021 Mar 15

PMID 33717036

Citations 36

Authors

Beatriz Merchel Piovesan Pereira

Xiaokang Wang

Ilias Tagkopoulos

Affiliations

Soon will be listed here.

Abstract

Significance Statement: Bacterial resistance and decreased susceptibility to antimicrobials is of utmost concern. There is evidence that improper biocide (antiseptic and disinfectant) use and discard may select for bacteria cross-resistant to antibiotics. Understanding the cross-resistance emergence and the risks associated with each of those chemicals is relevant for proper applications and recommendations. Our work establishes that not all biocides are equal when it comes to their risk of inducing antibiotic resistance; it provides evidence on the mechanisms of cross-resistance and a risk assessment of the biocides concerning antibiotic resistance under residual sub-inhibitory concentrations.

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