» Articles » PMID: 33680870

Cecal Endometriosis Presenting As a Term Intrauterine Fetal Demise and Gastrointestinal Hemorrhage: A Case Report

Overview
Date 2021 Mar 8
PMID 33680870
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Of women diagnosed with endometriosis, 3.8-37% have bowel endometriosis. The cecum is the least common site for endometriotic implants affecting the bowel, accounting for only 3.6-6% of cases. We present a case of intrauterine fetal demise at term in which the patient was found to have gastrointestinal bleeding caused by endometriosis of the cecum.

Case: A 35-year-old woman, gravida 4, para 1, at 37 weeks and 3 days of gestation, without a known history of endometriosis but with two prior miscarriages, presented with severe anemia and intrauterine fetal demise. During delivery, melanotic stool was noted. Colonoscopic biopsy noted the source of bleeding to be a 2 cm endometriotic implant in the patient's cecum. Suppression therapy was started. Postpartum, the patient underwent laparoscopic cecectomy and pathology confirmed the diagnosis of endometriosis.

Conclusion: Hemorrhage from endometriotic implants may occur during pregnancy due to changes in the hormonal milieu. Bowel endometriosis may increase the risk of maternal hemorrhage during pregnancy, thereby increasing the risk of unfavorable pregnancy outcomes, including intrauterine fetal demise.

Citing Articles

A Case of Rectal Endometriosis Misdiagnosed as Rectal Malignancy on Three Colonoscopies and Biopsies Sharing a Combined Literature Review.

Liang Y, Mei L, Ning Q, Zhang J, Fei J, Dong J Int J Womens Health. 2024; 16:163-174.

PMID: 38292299 PMC: 10826710. DOI: 10.2147/IJWH.S445280.


Endometriosis in the Cecum: A Rare Clinical Entity.

Verzoviti I, Kalliouris D, Boptsi A, Kiriakos N, Keramidaris D Cureus. 2023; 15(3):e35782.

PMID: 37025711 PMC: 10072167. DOI: 10.7759/cureus.35782.

References
1.
Nezhat C, Li A, Falik R, Copeland D, Razavi G, Shakib A . Bowel endometriosis: diagnosis and management. Am J Obstet Gynecol. 2017; 218(6):549-562. DOI: 10.1016/j.ajog.2017.09.023. View

2.
Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V . A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes. Hum Reprod Update. 2015; 22(1):70-103. DOI: 10.1093/humupd/dmv045. View

3.
Kao L, Tulac S, Lobo S, Imani B, Yang J, Germeyer A . Global gene profiling in human endometrium during the window of implantation. Endocrinology. 2002; 143(6):2119-38. DOI: 10.1210/endo.143.6.8885. View

4.
Stephansson O, Kieler H, Granath F, Falconer H . Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome. Hum Reprod. 2009; 24(9):2341-7. DOI: 10.1093/humrep/dep186. View

5.
Leone Roberti Maggiore U, Inversetti A, Schimberni M, Vigano P, Giorgione V, Candiani M . Obstetrical complications of endometriosis, particularly deep endometriosis. Fertil Steril. 2017; 108(6):895-912. DOI: 10.1016/j.fertnstert.2017.10.035. View