Anion Transport During Maturation of Erythroblastic Cells

Overview

Journal J Membr Biol

Date 1988 Jan 1

PMID 3367365

Citations 2

Authors

R G Kirk

P Lee

Affiliations

Soon will be listed here.

Abstract

Bromide uptake was measured in single maturing erythroblastic cells of rabbits by means of X-ray microanalysis. Increase in bromide uptake as the cells matured was observed. The order of cells from low to high bromide uptake was: early erythroblast less than late erythroblast less than marrow red cells less than peripheral red blood cells. The transition from low to high bromide uptake is correlated to the accumulation of iron which begins in the late erythroblast. A decrease in rubidium uptake also occurs as iron accumulates in the cell. These results indicate that the anion and cation transport changes during maturation are parallel in time course but opposite in direction. In addition, the increase in bromide uptake can be accounted for by the increase in surface-to-volume ratios of the cells. Surface-to-volume ratios were estimated by morphometric techniques.

Citing Articles

Transient increase in the alpha3-isoform of Na,K-ATPase in rat erythroblastic cells.

Chang C, Kirk R, Lee P Histochem J. 1999; 30(11):811-8.

PMID: 9988348 DOI: 10.1023/a:1003488306478.

Transport mechanisms for iron and other transition metals in rat and rabbit erythroid cells.

Savigni D, Morgan E J Physiol. 1998; 508 ( Pt 3):837-50.

PMID: 9518737 PMC: 2230914. DOI: 10.1111/j.1469-7793.1998.837bp.x.

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