Fibre Density, Amplitudes of Macro-EMG Motor Unit Potentials and Conventional EMG Recordings from the Anterior Tibial Muscle in Patients with Amyotrophic Lateral Sclerosis. A Study on 51 Cases

Overview

Journal J Neurol

Specialty Neurology

Date 1988 Jan 1

PMID 3367162

Citations 1

Authors

W Tackmann

P Vogel

Affiliations

Soon will be listed here.

Abstract

Fibre density and amplitudes of macro-EMG motor unit potentials were studied and compared with conventional EMG in the anterior tibial muscles from 51 patients with amyotrophic lateral sclerosis. The fibre density was increased in 46 muscles. Increased amplitudes of macro-EMG motor unit action potentials were found in 46 muscles, while the mean duration of motor unit potentials recorded with a concentric needle electrode was prolonged in only 26 muscles. Changes in the packing density of muscle fibres of surviving motor units are thought to influence the different electrophysiological parameters in different ways.

Citing Articles

A review of electrophysiological studies of lower motor neuron involvement in amyotrophic lateral sclerosis.

Amin Lari A, Ghavanini A, Bokaee H Neurol Sci. 2019; 40(6):1125-1136.

PMID: 30877611 DOI: 10.1007/s10072-019-03832-4.

References

Stalberg E, SCHWARTZ M, Trontelj J . Single fibre electromyography in various processes affecting the anterior horn cell. J Neurol Sci. 1975; 24(4):403-15. DOI: 10.1016/0022-510x(75)90166-5. View

Hilton-Brown P, Stalberg E . The motor unit in muscular dystrophy, a single fibre EMG and scanning EMG study. J Neurol Neurosurg Psychiatry. 1983; 46(11):981-95. PMC: 491734. DOI: 10.1136/jnnp.46.11.981. View

Ballantyne J, Hansen S . Computer method for the analysis of evoked motor unit potentials. I. Control subjects and patients with myasthenia gravis. J Neurol Neurosurg Psychiatry. 1974; 37(11):1187-94. PMC: 494882. DOI: 10.1136/jnnp.37.11.1187. View

Fawcett P, Johnson M, Schofield I . Comparison of electrophysiological and histochemical methods for assessing the spatial distribution of muscle fibres of a motor unit within muscle. J Neurol Sci. 1985; 69(1-2):67-79. DOI: 10.1016/0022-510x(85)90008-5. View

Wiechers D, Hubbell S . Late changes in the motor unit after acute poliomyelitis. Muscle Nerve. 1981; 4(6):524-8. DOI: 10.1002/mus.880040610. View

BUCHTHAL F, Pinelli P . Action potentials in muscular atrophy of neurogenic origin. Neurology. 1953; 3(8):591-603. DOI: 10.1212/wnl.3.8.591. View

COERS C, TELERMAN-TOPPET N, Gerard J . Terminal innervation ratio in neuromuscular disease. II. Disorders of lower motor neuron, peripheral nerve, and muscle. Arch Neurol. 1973; 29(4):215-22. DOI: 10.1001/archneur.1973.00490280027003. View

ERMINIO F, BUCHTHAL F, ROSENFALCK P . Motor unit territory and muscle fiber concentration in paresis due to peripheral nerve injury and anterior horn cell involvement. Neurology. 1959; 9:657-71. DOI: 10.1212/wnl.9.10.657. View

WOHLFART G . Collateral regeneration from residual motor nerve fibers in amyotrophic lateral sclerosis. Neurology. 1957; 7(2):124-34. DOI: 10.1212/wnl.7.2.124. View

10.

Stalberg E, Thiele B . Motor unit fibre density in the extensor digitorum communis muscle. Single fibre electromyographic study in normal subjects at different ages. J Neurol Neurosurg Psychiatry. 1975; 38(9):874-80. PMC: 492116. DOI: 10.1136/jnnp.38.9.874. View

11.

Nandedkar S, Stalberg E . Simulation of macro EMG motor unit potentials. Electroencephalogr Clin Neurophysiol. 1983; 56(1):52-62. DOI: 10.1016/0013-4694(83)90006-8. View

12.

Stalberg E . Macro EMG. Muscle Nerve. 1983; 6(9):619-30. DOI: 10.1002/mus.880060902. View

13.

TELERMAN-TOPPET N, COERS C . Motor innervation and fiber type pattern in amyotrophic lateral sclerosis and in Charcot-Marie-Tooth disease. Muscle Nerve. 1978; 1(2):133-9. DOI: 10.1002/mus.880010205. View

14.

McComas A, Sica R, Campbell M, Upton A . Functional compensation in partially denervated muscles. J Neurol Neurosurg Psychiatry. 1971; 34(4):453-60. PMC: 493831. DOI: 10.1136/jnnp.34.4.453. View

15.

SCHWARTZ M, Stalberg E, Swash M . Pattern of segmental motor involvement in syringomyelia: a single fibre EMG study. J Neurol Neurosurg Psychiatry. 1980; 43(2):150-5. PMC: 490490. DOI: 10.1136/jnnp.43.2.150. View

16.

Stalberg E, Fawcett P . Macro EMG in healthy subjects of different ages. J Neurol Neurosurg Psychiatry. 1982; 45(10):870-8. PMC: 491590. DOI: 10.1136/jnnp.45.10.870. View

17.

McComas A, Fawcett P, Campbell M, Sica R . Electrophysiological estimation of the number of motor units within a human muscle. J Neurol Neurosurg Psychiatry. 1971; 34(2):121-31. PMC: 493722. DOI: 10.1136/jnnp.34.2.121. View

18.

BUCHTHAL F, Pinelli P . Analysis of muscle action potentials as a diagnostic aid in neuro-muscular disorders. Acta Med Scand Suppl. 1952; 266:315-27. DOI: 10.1111/j.0954-6820.1952.tb13380.x. View

19.

Hansen S, Ballantyne J . A quantitative electrophysiological study of motor neurone disease. J Neurol Neurosurg Psychiatry. 1978; 41(9):773-83. PMC: 493153. DOI: 10.1136/jnnp.41.9.773. View

20.

Stalberg E . Macro EMG, a new recording technique. J Neurol Neurosurg Psychiatry. 1980; 43(6):475-82. PMC: 490586. DOI: 10.1136/jnnp.43.6.475. View