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Factors Affecting Metabolic Outcomes Post Bariatric Surgery: Role of Adipose Tissue

Overview
Journal J Clin Med
Specialty General Medicine
Date 2021 Mar 6
PMID 33670215
Citations 8
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Abstract

Obesity is an ever-growing public health crisis, and bariatric surgery (BS) has become a valuable tool in ameliorating obesity, along with comorbid conditions such as diabetes, dyslipidemia and hypertension. BS techniques have come a long way, leading to impressive improvements in the health of the majority of patients. Unfortunately, not every patient responds optimally to BS and there is no method that is sufficient to pre-operatively predict who will receive maximum benefit from this surgical intervention. This review focuses on the adipose tissue characteristics and related parameters that may affect outcomes, as well as the potential influences of insulin resistance, BMI, age, psychologic and genetic factors. Understanding the role of these factors may help predict who will benefit the most from BS.

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References
1.
Herder C, Peltonen M, Svensson P, Carstensen M, Jacobson P, Roden M . Adiponectin and bariatric surgery: associations with diabetes and cardiovascular disease in the Swedish Obese Subjects Study. Diabetes Care. 2014; 37(5):1401-9. DOI: 10.2337/dc13-1362. View

2.
Shin M, Hyun Y, Kim O, Kim J, Jang Y, Lee J . Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women. Int J Obes (Lond). 2006; 30(10):1529-34. DOI: 10.1038/sj.ijo.0803304. View

3.
Hosogai N, Fukuhara A, Oshima K, Miyata Y, Tanaka S, Segawa K . Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes. 2007; 56(4):901-11. DOI: 10.2337/db06-0911. View

4.
Broch M, Gomez J, Auguet M, Vilarrasa N, Pastor R, Elio I . Association of retinol-binding protein-4 (RBP4) with lipid parameters in obese women. Obes Surg. 2010; 20(9):1258-64. DOI: 10.1007/s11695-010-0200-5. View

5.
Hotamisligil G . Inflammation and metabolic disorders. Nature. 2006; 444(7121):860-7. DOI: 10.1038/nature05485. View