Fetal Cardiac Interventions-Are They Safe for the Mothers?

Overview

Journal J Clin Med

Specialty General Medicine

Date 2021 Mar 6

PMID 33669554

Citations 8

Authors

Beata Rebizant

Adam Kolesnik

Agnieszka Grzyb

Katarzyna Chaberek

Agnieszka Sekowska

Jacek Witwicki

Joanna Szymkiewicz-Dangel

Marzena Debska

Affiliations

Soon will be listed here.

Abstract

The aim of fetal cardiac interventions (FCI), as other prenatal therapeutic procedures, is to bring benefit to the fetus. However, the safety of the mother is of utmost importance. The objective of our study was to evaluate the impact of FCI on maternal condition, course of pregnancy, and delivery. 113 mothers underwent intrauterine treatment of their fetuses with critical heart defects. 128 percutaneous ultrasound-guided FCI were performed and analyzed. The patients were divided into four groups according to the type of FCI: balloon aortic valvuloplasty (fBAV), balloon pulmonary valvuloplasty (fBPV), interatrial stent placement (IAS), and balloon atrioseptoplasty (BAS). Various factors: maternal parameters, perioperative data, and pregnancy complications, were analyzed. There was only one major complication-procedure-related placental abruption (without need for blood products transfusion). There were no cases of: procedure-related preterm prelabor rupture of membranes (pPROM), chorioamnionitis, wound infection, and anesthesia associated complications. Tocolysis was only necessary only in two cases, and it was effective in both. None of the patients required intensive care unit admission. The procedure was effective in treating polyhydramnios associated with fetal heart failure in six out of nine cases. Deliveries occurred at term in 89%, 54% were vaginal. The results showed that FCI had a negligible impact on a further course of pregnancy and delivery.

Citing Articles

Impact of fetal pulmonary valvuloplasty in in-utero critical pulmonary stenosis: A systematic review and meta-analysis.

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Balloon Aortic Valvuloplasty in the Modern Era: A Review of Outcomes, Indications, and Technical Advances.

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Beyond Technical Success of Fetal Aortic Valvuloplasty.

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Catheter-Based Fetal Cardiac Interventions.

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Prognosis and outcome of intrauterine treatment of fetuses with critical congenital heart disease.

Zhao L, Wang L, Xia H, Wu Y, Jiao X, Zhu H Chin Med J (Engl). 2023; 137(12):1431-1436.

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