A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting As Severe Diabetic Ketoacidosis

Overview

Journal J Investig Med High Impact Case Rep

Specialty General Medicine

Date 2021 Feb 26

PMID 33631992

Citations 1

Authors

Krystal Mills

Judith Aniekwena

Tiffany Cochran

Echezona Nsofor

Nicolas Bakinde

Affiliations

Soon will be listed here.

Abstract

Primary hyperparathyroidism (PHPT) typically occurs in persons above 45 years, with a female predominance. PHPT induces a state of hypercalcemia, but acute pancreatitis is a rare sequelae of this hypercalcemia. We report a case of a 31-year-old man with no known medical history who presented in diabetic ketoacidosis with electrolyte abnormalities. His clinical course progressed to multi-organ dysfunction despite correction of metabolic derangements. Further workup led to the discovery of the uncommon triad by which previously undiagnosed PHPT precipitated severe diabetic ketoacidosis.

Citing Articles

Turning Points in Cross-Disciplinary Perspective of Primary Hyperparathyroidism and Pancreas Involvements: Hypercalcemia-Induced Pancreatitis, Gene-Related Tumors, and Insulin Resistance.

Carsote M, Nistor C, Gheorghe A, Sima O, Trandafir A, Nistor T Int J Mol Sci. 2024; 25(12).

PMID: 38928056 PMC: 11203827. DOI: 10.3390/ijms25126349.

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