» Articles » PMID: 33626415

Inflammatory Arthritis in Patients with COVID-19

Overview
Journal Transl Res
Publisher Elsevier
Specialty Pathology
Date 2021 Feb 24
PMID 33626415
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Patients with inflammatory arthritis represent a possible high-risk group to COVID-19 due to their immunosuppressive regimen designed to maintain low disease activity. Thus, substantial effort has been put forth to understand the impact of COVID-19 on these patients. Patients with rheumatic diseases as a whole do not appear to be more susceptible to acquiring COVID-19. Furthermore, immunosuppression generally did not increase the likelihood of developing severe COVID-19, with the important exception of medium and high-dose glucocorticoid use. In addition, a small number of COVID-19 patients have developed new inflammatory arthritis; whether this represents an unmasking of previous subclinical disease or a bone fide virus-induced arthritis is unclear. Nevertheless, it appears that inflammatory arthritis patients currently on immunosuppression should continue their medication to prevent future flares and limit glucocorticoid usage. While this continues to be a rapidly evolving field, these data are reassuring to both patients with and providers treating inflammatory arthritides.

Citing Articles

Covid-19-related right hip monoarthritis: A case report and literature review.

Ismael A, Yves-Zakari K, Tchenadoyo B, Mamadou B, Nadege Y, Aziz A Clin Case Rep. 2024; 12(1):e8462.

PMID: 38268619 PMC: 10805996. DOI: 10.1002/ccr3.8462.


A case of de novo seronegative inflammatory oligoarthritis associated with COVID-19 infection.

Sung L, Surmachevska N, Rubio J Clin Immunol Commun. 2023; 2:159-161.

PMID: 38013974 PMC: 9580240. DOI: 10.1016/j.clicom.2022.10.001.


Acute COVID-Related Hip Arthritis. Case Report and Literature Review.

Kalavrytinos D, Kosmidis I J Orthop Case Rep. 2023; 13(6):40-43.

PMID: 37398528 PMC: 10308990. DOI: 10.13107/jocr.2023.v13.i06.3688.


Can hydroxychloroquine be used for COVID-19-induced arthritis? A debatable hypothesis.

Swarnakar R, Roy S, Yadav S World J Exp Med. 2022; 12(6):108-110.

PMID: 36560976 PMC: 9764691. DOI: 10.5493/wjem.v12.i6.108.


Evaluating Risk: Benefit Ratio of Fat-Soluble Vitamin Supplementation to SARS-CoV-2-Infected Autoimmune and Cancer Patients: Do Vitamin-Drug Interactions Exist?.

Mekky R, Elemam N, Eltahtawy O, Zeinelabdeen Y, Youness R Life (Basel). 2022; 12(10).

PMID: 36295089 PMC: 9604733. DOI: 10.3390/life12101654.


References
1.
Mokuda S, Tokunaga T, Masumoto J, Sugiyama E . Angiotensin-converting Enzyme 2, a SARS-CoV-2 Receptor, Is Upregulated by Interleukin 6 through STAT3 Signaling in Synovial Tissues. J Rheumatol. 2020; 47(10):1593-1595. DOI: 10.3899/jrheum.200547. View

2.
Haberman R, Castillo R, Chen A, Yan D, Ramirez D, Sekar V . COVID-19 in Patients With Inflammatory Arthritis: A Prospective Study on the Effects of Comorbidities and Disease-Modifying Antirheumatic Drugs on Clinical Outcomes. Arthritis Rheumatol. 2020; 72(12):1981-1989. PMC: 7722024. DOI: 10.1002/art.41456. View

3.
Mikuls T, Johnson S, Fraenkel L, Arasaratnam R, Baden L, Bermas B . American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID-19 Pandemic: Version 2. Arthritis Rheumatol. 2020; 72(9):e1-e12. DOI: 10.1002/art.41437. View

4.
Joo Y, Lim Y, Kim K, Park K, Park Y . Respiratory viral infections and the risk of rheumatoid arthritis. Arthritis Res Ther. 2019; 21(1):199. PMC: 6716891. DOI: 10.1186/s13075-019-1977-9. View

5.
Soden M, Vasudevan H, Roberts B, Coelen R, Hamlin G, Vasudevan S . Detection of viral ribonucleic acid and histologic analysis of inflamed synovium in Ross River virus infection. Arthritis Rheum. 2000; 43(2):365-9. DOI: 10.1002/1529-0131(200002)43:2<365::AID-ANR16>3.0.CO;2-E. View