Decreased Antibiotic Susceptibility in Surviving UV Irradition

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2021 Feb 22

PMID 33613479

Citations 2

Authors

Hai-Bei Li

Ai-Ming Hou

Tian-Jiao Chen

Dong Yang

Zheng-Shan Chen

Zhi-Qiang Shen

Zhi-Gang Qiu

Jing Yin

Zhong-Wei Yang

Dan-Yang Shi

Hua-Ran Wang

Jun-Wen Li

Min Jin

Affiliations

Soon will be listed here.

Abstract

Given its excellent performance against the pathogens, UV disinfection has been applied broadly in different fields. However, only limited studies have comprehensively investigated the response of bacteria surviving UV irradiation to the environmental antibiotic stress. Here, we investigated the antibiotic susceptibility of suffering from the UV irradiation. Our results revealed that UV exposure may decrease the susceptibility to tetracycline, ciprofloxacin, and polymyxin B in the survival . Mechanistically, UV exposure causes oxidative stress in and consequently induces dysregulation of genes contributed to the related antibiotic resistance genes. These results revealed that the insufficient ultraviolet radiation dose may result in the decreased antibiotic susceptibility in the pathogens, thus posing potential threats to the environment and human health.

Citing Articles

Occurrence and Treatment of Antibiotic-Resistant Bacteria Present in Surface Water.

Serio J, Marques A, Huertas R, Crespo J, Pereira V Membranes (Basel). 2023; 13(4).

PMID: 37103852 PMC: 10141635. DOI: 10.3390/membranes13040425.

Antimicrobials and Food-Related Stresses as Selective Factors for Antibiotic Resistance along the Farm to Fork Continuum.

Giacometti F, Shirzad-Aski H, Ferreira S Antibiotics (Basel). 2021; 10(6).

PMID: 34199740 PMC: 8230312. DOI: 10.3390/antibiotics10060671.

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