Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine Applications

Overview

Journal Recent Prog Mater

Date 2021 Feb 19

PMID 33604591

Citations 2

Authors

Emma G Norris

Diane Dalecki

Denise C Hocking

Affiliations

Soon will be listed here.

Abstract

Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracellular matrix scaffolds both directly, and indirectly via biochemical and cellular mediators. Materials derived from components of native extracellular matrix are an essential component of engineered biomaterials designed to stimulate cell and tissue functions and repair or replace injured tissues. Thus, continued investigations into biological and acoustic mechanisms by which ultrasound can be used to manipulate extracellular matrix components within three-dimensional hydrogels hold much potential to enable the production of improved biomaterials for clinical and research applications.

Citing Articles

Exploring the Potential of Ultrasound Therapy to Reduce Skin Scars: An In Vitro Study Using a Multi-Well Device Based on Printable Piezoelectric Transducers.

Porsborg S, Krzyslak H, Pierchala M, Trole V, Astafiev K, Lou-Moeller R Bioengineering (Basel). 2023; 10(5).

PMID: 37237636 PMC: 10215462. DOI: 10.3390/bioengineering10050566.

Ultrasound-Induced Drug Release from Stimuli-Responsive Hydrogels.

Yeingst T, Arrizabalaga J, Hayes D Gels. 2022; 8(9).

PMID: 36135267 PMC: 9498906. DOI: 10.3390/gels8090554.

References

Dalecki D . Mechanical bioeffects of ultrasound. Annu Rev Biomed Eng. 2004; 6:229-48. DOI: 10.1146/annurev.bioeng.6.040803.140126. View

Demidova-Rice T, Hamblin M, Herman I . Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care. Adv Skin Wound Care. 2012; 25(7):304-14. PMC: 3428147. DOI: 10.1097/01.ASW.0000416006.55218.d0. View

Suslick K . Sonochemistry. Science. 1990; 247(4949):1439-45. DOI: 10.1126/science.247.4949.1439. View

Apfel R, Holland C . Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound. Ultrasound Med Biol. 1991; 17(2):179-85. DOI: 10.1016/0301-5629(91)90125-g. View

Martin-Saavedra F, Wilson C, Voellmy R, Vilaboa N, Franceschi R . Spatiotemporal control of vascular endothelial growth factor expression using a heat-shock-activated, rapamycin-dependent gene switch. Hum Gene Ther Methods. 2013; 24(3):160-70. PMC: 3732131. DOI: 10.1089/hgtb.2013.026. View

Yuan H, Hu H, Sun J, Shi M, Yu H, Li C . Ultrasound Microbubble Delivery Targeting Intraplaque Neovascularization Inhibits Atherosclerotic Plaque in an APOE-deficient Mouse Model. In Vivo. 2018; 32(5):1025-1032. PMC: 6199608. DOI: 10.21873/invivo.11342. View

Ghanem M, Maxwell A, Sapozhnikov O, Khokhlova V, Bailey M . QUANTIFICATION OF ACOUSTIC RADIATION FORCES ON SOLID OBJECTS IN FLUID. Phys Rev Appl. 2020; 12(4). PMC: 7050195. DOI: 10.1103/physrevapplied.12.044076. View

Sundelacruz S, Kaplan D . Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine. Semin Cell Dev Biol. 2009; 20(6):646-55. PMC: 2737137. DOI: 10.1016/j.semcdb.2009.03.017. View

Sottile J, Shi F, Rublyevska I, Chiang H, Lust J, Chandler J . Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin. Am J Physiol Cell Physiol. 2007; 293(6):C1934-46. DOI: 10.1152/ajpcell.00130.2007. View

10.

Abou Neel E, Bozec L, Knowles J, Syed O, Mudera V, Day R . Collagen--emerging collagen based therapies hit the patient. Adv Drug Deliv Rev. 2012; 65(4):429-56. DOI: 10.1016/j.addr.2012.08.010. View

11.

Schultz G, Wysocki A . Interactions between extracellular matrix and growth factors in wound healing. Wound Repair Regen. 2009; 17(2):153-62. DOI: 10.1111/j.1524-475X.2009.00466.x. View

12.

Nele V, Schutt C, Wojciechowski J, Kit-Anan W, Doutch J, Armstrong J . Ultrasound-Triggered Enzymatic Gelation. Adv Mater. 2020; 32(7):e1905914. PMC: 7180077. DOI: 10.1002/adma.201905914. View

13.

Lanfer B, Seib F, Freudenberg U, Stamov D, Bley T, Bornhauser M . The growth and differentiation of mesenchymal stem and progenitor cells cultured on aligned collagen matrices. Biomaterials. 2009; 30(30):5950-8. DOI: 10.1016/j.biomaterials.2009.07.039. View

14.

Williams R, Zipfel W, Webb W . Interpreting second-harmonic generation images of collagen I fibrils. Biophys J. 2004; 88(2):1377-86. PMC: 1305140. DOI: 10.1529/biophysj.104.047308. View

15.

Badylak S . Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl Immunol. 2004; 12(3-4):367-77. DOI: 10.1016/j.trim.2003.12.016. View

16.

Vishwanath V, Frank K, Elmets C, Dauchot P, Monnier V . Glycation of skin collagen in type I diabetes mellitus. Correlation with long-term complications. Diabetes. 1986; 35(8):916-21. DOI: 10.2337/diab.35.8.916. View

17.

Bader K, Gruber M, Holland C . Shaken and stirred: mechanisms of ultrasound-enhanced thrombolysis. Ultrasound Med Biol. 2014; 41(1):187-96. PMC: 4258471. DOI: 10.1016/j.ultrasmedbio.2014.08.018. View

18.

Dong X, Lu X, Kingston K, Brewer E, Juliar B, Kripfgans O . Controlled delivery of basic fibroblast growth factor (bFGF) using acoustic droplet vaporization stimulates endothelial network formation. Acta Biomater. 2019; 97:409-419. PMC: 6801030. DOI: 10.1016/j.actbio.2019.08.016. View

19.

Voytik-Harbin S, Brightman A, Kraine M, Waisner B, Badylak S . Identification of extractable growth factors from small intestinal submucosa. J Cell Biochem. 1998; 67(4):478-91. View

20.

Ino K, Okochi M, Honda H . Application of magnetic force-based cell patterning for controlling cell-cell interactions in angiogenesis. Biotechnol Bioeng. 2008; 102(3):882-90. DOI: 10.1002/bit.22104. View