Non-human Primates and Immunity

Overview

Journal Cytokine X

Date 2021 Feb 19

PMID 33604562

Citations 3

Authors

Sonia Andre

Vasco Rodrigues

Morgane Picard

Ricardo Silvestre

Jerome Estaquier

Affiliations

Soon will be listed here.

Abstract

In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus and classified as one of the neglected tropical diseases.

Citing Articles

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References

Gicheru M, Olobo J, Kariuki T, Adhiambo C . Visceral leishmaniasis in vervet monkeys: immunological responses during asymptomatic infections. Scand J Immunol. 1995; 41(2):202-8. DOI: 10.1111/j.1365-3083.1995.tb03554.x. View

Amaral V, Teva A, Porrozzi R, Silva A, Pereira M, Oliveira-Neto M . Leishmania (Leishmania) major-infected rhesus macaques (Macaca mulatta) develop varying levels of resistance against homologous re-infections. Mem Inst Oswaldo Cruz. 2001; 96(6):795-804. DOI: 10.1590/s0074-02762001000600010. View

Berman J, Hanson W, Chapman W, Alving C, Lopez-Berestein G . Antileishmanial activity of liposome-encapsulated amphotericin B in hamsters and monkeys. Antimicrob Agents Chemother. 1986; 30(6):847-51. PMC: 180605. DOI: 10.1128/AAC.30.6.847. View

Silvestri G, Sodora D, Koup R, Paiardini M, ONeil S, McClure H . Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity. 2003; 18(3):441-52. DOI: 10.1016/s1074-7613(03)00060-8. View

Thacker S, McWilliams I, Bonnet B, Halie L, Beaucage S, Rachuri S . CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis. PLoS Negl Trop Dis. 2020; 14(2):e0008050. PMC: 7075640. DOI: 10.1371/journal.pntd.0008050. View

Lewis M, Paun A, Romano A, Langston H, Langner C, Moore I . Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis. PLoS Pathog. 2020; 16(4):e1008456. PMC: 7179947. DOI: 10.1371/journal.ppat.1008456. View

Porrozzi R, Pereira M, Teva A, Volpini A, Pinto M, Marchevsky R . Leishmania infantum-induced primary and challenge infections in rhesus monkeys (Macaca mulatta): a primate model for visceral leishmaniasis. Trans R Soc Trop Med Hyg. 2006; 100(10):926-37. DOI: 10.1016/j.trstmh.2005.11.005. View

Rodrigues V, Cordeiro-da-Silva A, Laforge M, Ouaissi A, Akharid K, Silvestre R . Impairment of T cell function in parasitic infections. PLoS Negl Trop Dis. 2014; 8(2):e2567. PMC: 3923671. DOI: 10.1371/journal.pntd.0002567. View

Lawyer P, Githure J, Anjili C, Olobo J, Koech D, Reid G . Experimental transmission of Leishmania major to vervet monkeys (Cercopithecus aethiops) by bites of Phlebotomus duboscqi (Diptera: Psychodidae). Trans R Soc Trop Med Hyg. 1990; 84(2):229-32. DOI: 10.1016/0035-9203(90)90266-h. View

10.

Freidag B, Mendez S, Cheever A, Kenney R, Flynn B, Sacks D . Immunological and pathological evaluation of rhesus macaques infected with Leishmania major. Exp Parasitol. 2003; 103(3-4):160-8. DOI: 10.1016/s0014-4894(03)00099-7. View

11.

van Griensven J, Diro E, Lopez-Velez R, Ritmeijer K, Boelaert M, Zijlstra E . A screen-and-treat strategy targeting visceral leishmaniasis in HIV-infected individuals in endemic East African countries: the way forward?. PLoS Negl Trop Dis. 2014; 8(8):e3011. PMC: 4125108. DOI: 10.1371/journal.pntd.0003011. View

12.

Zotos D, Coquet J, Zhang Y, Light A, DCosta K, Kallies A . IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med. 2010; 207(2):365-78. PMC: 2822601. DOI: 10.1084/jem.20091777. View

13.

Olobo J, Reid G . Mitogenic responses of peripheral blood mononuclear cells of vervet monkeys (Cercopithecus aethiops): Apparent role of adherent cells. Am J Primatol. 2020; 20(1):31-36. DOI: 10.1002/ajp.1350200105. View

14.

Misra A, Dube A, Naik S . Immune responses in normal Indian langur monkeys (Presbytis entellus)--a primate model for visceral leishmaniasis. J Med Primatol. 2004; 33(2):65-9. DOI: 10.1111/j.1600-0684.2004.00045.x. View

15.

Souza-Lemos C, de-Campos S, Teva A, Porrozzi R, Grimaldi Jr G . In situ characterization of the granulomatous immune response with time in nonhealing lesional skin of Leishmania braziliensis-infected rhesus macaques (Macaca mulatta). Vet Immunol Immunopathol. 2011; 142(3-4):147-55. DOI: 10.1016/j.vetimm.2011.05.002. View

16.

Olobo J, Reid G . Delayed-type hypersensitivity responses in vervet monkeys self-cured from experimental cutaneous leishmaniasis. Acta Trop. 1993; 52(4):309-11. DOI: 10.1016/0001-706x(93)90015-4. View

17.

Teva A, Porrozzi R, Cupolillo E, Pirmez C, Oliveira-Neto M, Grimaldi Jr G . Leishmania (Viannia) braziliensis-induced chronic granulomatous cutaneous lesions affecting the nasal mucosa in the rhesus monkey (Macaca mulatta) model. Parasitology. 2003; 127(Pt 5):437-47. DOI: 10.1017/s0031182003004037. View

18.

Campos-Neto A, Porrozzi R, Greeson K, Coler R, Webb J, Seiky Y . Protection against cutaneous leishmaniasis induced by recombinant antigens in murine and nonhuman primate models of the human disease. Infect Immun. 2001; 69(6):4103-8. PMC: 98475. DOI: 10.1128/IAI.69.6.4103-4108.2001. View

19.

Nurieva R, Chung Y, Martinez G, Yang X, Tanaka S, Matskevitch T . Bcl6 mediates the development of T follicular helper cells. Science. 2009; 325(5943):1001-5. PMC: 2857334. DOI: 10.1126/science.1176676. View

20.

Chapman Jr W, Hanson W, Hendricks L . Leishmania donovani in the owl monkey (aotus trivirgatus). Trans R Soc Trop Med Hyg. 1981; 75(1):124-5. DOI: 10.1016/0035-9203(81)90032-8. View