Mitochondrial Calcification

Overview

Journal Immunometabolism

Date 2021 Feb 19

PMID 33604080

Citations 11

Authors

Bhargavi Duvvuri

Christian Lood

Affiliations

Soon will be listed here.

Abstract

One of the most fascinating aspects of mitochondria is their remarkable ability to accumulate and store large amounts of calcium in the presence of phosphate leading to mitochondrial calcification. In this paper, we briefly address the mechanisms that regulate mitochondrial calcium homeostasis followed by the extensive review on the formation and characterization of intramitochondrial calcium phosphate granules leading to mitochondrial calcification and its relevance to physiological and pathological calcifications of body tissues.

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