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Atypical Site of Venous Thrombosis Despite Appropriate Anticoagulation in a Patient with Myeloproliferative Neoplasm

Overview
Journal Maedica (Bucur)
Specialty General Medicine
Date 2021 Feb 19
PMID 33603913
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Abstract

The following case report and literature review will emphasize the individualized therapeutic management of a complex prothrombotic pathology. The onset of acute portal vein thrombosis in a patient with atrial fibrillation and good compliance to anticoagulation with a direct oral anticoagulant, who associates significant thrombocytosis, after excluding predisposing inflammations, infections or solid neoplasia, raises the diagnostic suspicion of myeloproliferative disorder, and imposes a complex interdisciplinary approach.

References
1.
Reikvam H, Tiu R . Venous thromboembolism in patients with essential thrombocythemia and polycythemia vera. Leukemia. 2011; 26(4):563-71. DOI: 10.1038/leu.2011.314. View

2.
Kreher S, Ochsenreither S, Trappe R, Pabinger I, Bergmann F, Petrides P . Prophylaxis and management of venous thromboembolism in patients with myeloproliferative neoplasms: consensus statement of the Haemostasis Working Party of the German Society of Hematology and Oncology (DGHO), the Austrian Society of Hematology and.... Ann Hematol. 2014; 93(12):1953-63. DOI: 10.1007/s00277-014-2224-8. View

3.
Konstantinides S, Meyer G, Becattini C, Bueno H, Geersing G, Harjola V . 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2019; 41(4):543-603. DOI: 10.1093/eurheartj/ehz405. View

4.
Janczak D, Mimier M, McBane R, Kamath P, Simmons B, Bott-Kitslaar D . Rivaroxaban and Apixaban for Initial Treatment of Acute Venous Thromboembolism of Atypical Location. Mayo Clin Proc. 2017; 93(1):40-47. DOI: 10.1016/j.mayocp.2017.10.007. View

5.
Agnelli G, Becattini C, Meyer G, Munoz A, Huisman M, Connors J . Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer. N Engl J Med. 2020; 382(17):1599-1607. DOI: 10.1056/NEJMoa1915103. View