One Bout of Aerobic Exercise Can Enhance the Expression of in Oxidative Skeletal Muscle Samples

Overview

Journal Front Physiol

Date 2021 Feb 18

PMID 33597895

Citations 5

Authors

Rafael L Rovina

Alisson L da Rocha

Bruno B Marafon

Jose R Pauli

Leandro P de Moura

Dennys E Cintra

Eduardo R Ropelle

Adelino S R DA Silva

Affiliations

Soon will be listed here.

Abstract

The nuclear receptor subfamily 1, group D member 1 (, plays a role in the skeletal muscle's oxidative capacity, mitochondrial biogenesis, atrophy genes, and muscle fiber size. In light of the effects of physical exercise, the present study investigates the acute response of and genes related to atrophy and mitochondrial biogenesis on endurance and resistance exercise protocols. In this investigation, we observed, after one bout of endurance exercise, an upregulation of in soleus muscle, but not in the gastrocnemius, and some genes related to mitochondrial biogenesis and atrophy were enhanced as well. Also, analysis of muscle transcripts from diverse isogenic BXD mice families revealed that the strains with higher gene expression displayed upregulation of AMPK signaling and mitochondrial-related genes. In summary, a single session of endurance exercise can enhance the mRNA levels in an oxidative muscle.

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