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Step-by-step Surgical Procedures for a Correct Identification of the Sentinel Lymph Node in Endometrial Cancer

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Date 2021 Feb 12
PMID 33575680
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Abstract

Background: In patients with endometrial cancer, the common method for assessing the status of lymph nodes (LN) is lymphadenectomy. The sentinel lymph node (SLN) biopsy is a revolutionary concept and it will play an increasingly important role in surgical practice. The surgical technique of the sentinel lymph node is less destructive than lymphadenectomy, and it requires less anatomical knowledge.

Methods: Step by step technique of cervical injection, the preparation of the anatomical spaces and the identification of the main structures to detect and remove the SLN safely in patients affected by endometrial cancer stage IA.

Results: We identify the three different lymphatic pathways drainage from the uterine cervix and show how anatomical retroperitoneal knowledge is essential for the safe dissection of anatomical spaces. In literature it is reported that in about 9% of cases the SLN is located at the lumbo-aortic level, so it is clear how important it is to know the anatomy to follow the highlighted lymph pathway to identify first lymph node absorber of the drainage.

Conclusion: Anatomical knowledge and the correct preparation of the anatomical spaces make the identification of the sentinel lymph node safe and feasible.

References
1.
Ercoli A, Delmas V, Iannone V, Fagotti A, Fanfani F, Corrado G . The lymphatic drainage of the uterine cervix in adult fresh cadavers: anatomy and surgical implications. Eur J Surg Oncol. 2009; 36(3):298-303. DOI: 10.1016/j.ejso.2009.06.009. View

2.
Rozenholc A, Samouelian V, Warkus T, Gauthier P, Provencher D, Sauthier P . Green versus blue: Randomized controlled trial comparing indocyanine green with methylene blue for sentinel lymph node detection in endometrial cancer. Gynecol Oncol. 2019; 153(3):500-504. DOI: 10.1016/j.ygyno.2019.03.103. View

3.
Khoury-Collado F, Clair C, Abu-Rustum N . Sentinel Lymph Node Mapping in Endometrial Cancer: An Update. Oncologist. 2016; 21(4):461-6. PMC: 4828124. DOI: 10.1634/theoncologist.2015-0473. View

4.
Schlappe B, Weaver A, Ducie J, Zahl Eriksson A, Dowdy S, Cliby W . Multicenter study comparing oncologic outcomes between two nodal assessment methods in patients with deeply invasive endometrioid endometrial carcinoma: A sentinel lymph node algorithm versus a comprehensive pelvic and paraaortic lymphadenectomy. Gynecol Oncol. 2018; 151(2):235-242. PMC: 6214768. DOI: 10.1016/j.ygyno.2018.08.022. View

5.
Leitao Jr M, Zhou Q, Gomez-Hidalgo N, Iasonos A, Baser R, Mezzancello M . Patient-reported outcomes after surgery for endometrial carcinoma: Prevalence of lower-extremity lymphedema after sentinel lymph node mapping versus lymphadenectomy. Gynecol Oncol. 2019; 156(1):147-153. PMC: 6980687. DOI: 10.1016/j.ygyno.2019.11.003. View