Why Not Have Definitive Trials of Gastrointestinal Safety for Non-steroidal Anti-inflammatory Drugs? Discussion Paper

Overview

Journal J R Soc Med

Specialty General Medicine

Date 1988 Mar 1

PMID 3357159

Citations 1

Authors

D Clinch

Affiliations

Soon will be listed here.

Citing Articles

[Not Available].

Grondin C Can Fam Physician. 2011; 36:487-99.

PMID: 21234065 PMC: 2280671.

References

Collier D, Pain J . Non-steroidal anti-inflammatory drugs and peptic ulcer perforation. Gut. 1985; 26(4):359-63. PMC: 1432521. DOI: 10.1136/gut.26.4.359. View

Clinch D, Banerjee A, Ostick G . Absence of abdominal pain in elderly patients with peptic ulcer. Age Ageing. 1984; 13(2):120-3. DOI: 10.1093/ageing/13.2.120. View

Allan R, Dykes P . A study of the factors influencing mortality rates from gastrointestinal haemorrhage. Q J Med. 1976; 45(180):533-50. View

KERN Jr F, Clark G, LUKENS J . Peptic ulceration occurring during therapy for rheumatoid arthritis. Gastroenterology. 1957; 33(1):25-33. View

VAKIL B, Shah P, Dalal N, Wagholikar U, Pispati P . Endoscopic study of gastro-intestinal injury with non-steroidal anti-inflammatory drugs. Curr Med Res Opin. 1977; 5(1):38-42. DOI: 10.1185/03007997709108974. View

Clinch D, Banerjee A, LEVY D, Ostick G, Faragher E . Non-steroidal anti-inflammatory drugs and peptic ulceration. J R Coll Physicians Lond. 1987; 21(3):183-7. PMC: 5379336. View

Elashoff J, GROSSMAN M . Trends in hospital admissions and death rates for peptic ulcer in the United States from 1970 to 1978. Gastroenterology. 1980; 78(2):280-5. View

Jick H, Vessey M . Case-control studies in the evaluation of drug-induced illness. Am J Epidemiol. 1978; 107(1):1-7. DOI: 10.1093/oxfordjournals.aje.a112502. View

COHEN M . Treatment and mortality of perforated peptic ulcer: a survey of 852 cases. Can Med Assoc J. 1971; 105(3):263-9 passim. PMC: 1931129. View

10.

Pemberton R, STRAND L . A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Dig Dis Sci. 1979; 24(1):53-64. DOI: 10.1007/BF01297239. View

11.

Hill A . THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION?. Proc R Soc Med. 1965; 58:295-300. PMC: 1898525. DOI: 10.1177/003591576505800503. View

12.

Kurata J, Elashoff J, GROSSMAN M . Inadequacy of the literature on the relationship between drugs, ulcers, and gastrointestinal bleeding. Gastroenterology. 1982; 82(2):373-6. View

13.

Trewby P . Drug-induced peptic ulcer and upper gastrointestinal bleeding. Br J Hosp Med. 1980; 23(2):185-8, 190. View

14.

Lanza F, Umbenhauer E, Nelson R, Rack M, Daurio C, White L . A double-blind randomized placebo controlled gastroscopic study to compare the effects of indomethacin capsules and indomethacin suppositories on the gastric mucosa of human volunteers. J Rheumatol. 1982; 9(3):415-9. View

15.

Bonnevie O . The incidence of gastric ulcer in Copenhagen county. Scand J Gastroenterol. 1975; 10(3):231-9. View

16.

Levy M . Aspirin use in patients with major upper gastrointestinal bleeding and peptic-ulcer disease. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center. N Engl J Med. 1974; 290(21):1158-62. DOI: 10.1056/NEJM197405232902102. View

17.

Stephens F, Lawrenson K . 51Cr Excretion in bile. Lancet. 1969; 1(7586):158-9. DOI: 10.1016/s0140-6736(69)91175-1. View

18.

Lanza F, Royer Jr G, Nelson R, Chen T, Seckman C, Rack M . The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study. Dig Dis Sci. 1979; 24(11):823-8. DOI: 10.1007/BF01324896. View

19.

Slater T, Delaney V . Liver adenosine triphosphate content and bile flow rate in the rat. Biochem J. 1970; 116(2):303-8. PMC: 1185359. DOI: 10.1042/bj1160303. View