A Retrospective Analysis of the Impact of Bariatric Surgery on the Management of Chronic Migraine

Overview

Journal Obes Surg

Date 2021 Feb 11

PMID 33569730

Citations 1

Authors

Richard Nudotor

Hasiya Yusuf

Owulatobi Lasisi

Emmanuella Salia

Banda Khalifa

Enoch Abbey

Modupe Oduwole

Samuel Ayeh

Obeng Appiafo

Joseph Canner

Ann Scheimann

Kimberley E Steele

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate the association of the two most common bariatric surgical procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), with sustained remission from chronic migraine.

Materials And Methods: Using IBM MarketScan® research database to examine inpatient and pharmacy claims from 2010 through 2017. A cohort of bariatric patients with chronic migraine was created using inclusion and exclusion criteria. Remission was defined as no refill of first-line migraine medication for 180 days after a patients' medication was expected to run out, and recurrence as medication refill after at least 180 days of remission.

Results: Of 1680 patients in our cohort, 931 (55.4%) experienced remission of migraine. Of these, 462 (49.6%) had undergone VSG, while 469 (50.4%) had undergone RYGB. Patients who underwent RYGB had an 11% (RR = 1.11, 95% CI: 1.05, 1.17) increase in likelihood of remission of migraine and a 20% (RR = 0.80, 95% CI: 0.63, 1.04) decrease in likelihood of recurrence of migraine compared to patients who underwent VSG. Older age group, higher number of medications at time of surgery, and female sex were associated with a decreased likelihood of remission.

Conclusion: Type of bariatric procedure, age, number of medications at surgery, and sex were the most important predictors of migraine remission after surgery.

Citing Articles

Bariatric Surgery in Migraine patients: CGRP Level and Weight Loss.

Etefagh H, Shahmiri S, Melali H, Sayadi M, Ansari H, Shahzamani A Obes Surg. 2022; 32(11):3635-3640.

PMID: 35922609 DOI: 10.1007/s11695-022-06218-2.

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