» Articles » PMID: 33563732

Microbiome: Role and Functionality in Human Nutrition Cycle

Overview
Journal Saudi Med J
Specialty General Medicine
Date 2021 Feb 10
PMID 33563732
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Microbes are present almost everywhere on this Earth. Humans harbor microbes in various organs, including skin, gut, mouth, and nose. Among these, the gut region has the highest population of microbes. Gut microbiota is directly linked with homeostasis, and a minor change in their numbers predisposes humans to ailments. Notably, the role of the microbial population in the digestive tract directly contributes to body weight. Sometimes, lifestyle changes or antibiotics intake to manage certain infections are associated with disturbance in the gut microflora. Several scientific studies allude to the obesity linkage with disturbed intestinal microflora. This review mainly focuses on how healthy nutrition contributes towards maintaining normal flora inside the human body. Importantly, the contribution of probiotics and prebiotics in maintaining human healthy body weight is discussed.

Citing Articles

Influence of Supplementation on the Glycaemic Index, Lipid Profile, and Microbiome of Healthy Elderly Subjects: A Preliminary Randomized Clinical Trial.

Chaiyasut C, Sivamaruthi B, Thangaleela S, Sisubalan N, Bharathi M, Khongtan S Foods. 2024; 13(9).

PMID: 38731665 PMC: 11083618. DOI: 10.3390/foods13091293.


Effects of Probiotic Use on Gastrointestinal Symptoms in the Late Postoperative Period of Bariatric Surgery: A Cross-Over, Randomized, Triple-Blind, Placebo-Controlled Study.

Wagner N, Lopes M, Fernandes R, Taconelli C, Nascimento G, Pessini J Obes Surg. 2024; 34(4):1306-1315.

PMID: 38418752 DOI: 10.1007/s11695-024-07117-4.

References
1.
Levy R, Magis A, Earls J, Manor O, Wilmanski T, Lovejoy J . Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome. Proc Natl Acad Sci U S A. 2020; 117(24):13839-13845. PMC: 7306764. DOI: 10.1073/pnas.1922498117. View

2.
Nakamura T, Fahmi M, Tanaka J, Seki K, Kubota Y, Ito M . Genome-Wide Analysis of Whole Human Glycoside Hydrolases by Data-Driven Analysis in Silico. Int J Mol Sci. 2019; 20(24). PMC: 6940844. DOI: 10.3390/ijms20246290. View

3.
van den Elsen L, Garssen J, Burcelin R, Verhasselt V . Shaping the Gut Microbiota by Breastfeeding: The Gateway to Allergy Prevention?. Front Pediatr. 2019; 7:47. PMC: 6400986. DOI: 10.3389/fped.2019.00047. View

4.
Barton W, OSullivan O, Cotter P . Metabolic phenotyping of the human microbiome. F1000Res. 2019; 8. PMC: 6880276. DOI: 10.12688/f1000research.19481.1. View

5.
Khan M, Gerasimidis K, Edwards C, Shaikh M . Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature. J Obes. 2016; 2016:7353642. PMC: 5040794. DOI: 10.1155/2016/7353642. View