Lumpy Skin Disease Outbreaks in Vietnam, 2020

Overview

Journal Transbound Emerg Dis

Specialty Veterinary Medicine

Date 2021 Feb 6

PMID 33548101

Citations 42

Authors

Ha Thi Thanh Tran

Anh Duc Truong

Anh Kieu Dang

Duc Viet Ly

Chinh Thi Nguyen

Nhu Thi Chu

Tuan Van Hoang

Huyen Thi Nguyen

Vinh The Nguyen

Hoang Vu Dang

Affiliations

Soon will be listed here.

Abstract

Lumpy skin disease (LSD) is a transboundary, systemic, viral disease of cattle. The first outbreaks of LSD were reported in Lang Son Province of Vietnam (bordered to China), and an official document has been submitted to OIE on 1 November 2020. Here, we described first the genetic profiles of this pathogen based on four well-known marker regions. The LSD virus isolated in these first outbreaks was 100% identical to viruses isolated in China (2019) based on the p32 and RP030 genes. Additionally, it is very close to the virus isolated in Russia (2017) based on the p32, RP030, thymidine kinase and ORF103 genes (100%, 99.01%, 99.08% and 99.47% identities). This finding is new, and a success in LSD virus isolation using MDBK cells from first outbreaks is important for vaccine development to control and eradicate LSD in Vietnam.

Citing Articles

Genetic characterization of lumpy skin disease virus (LSDV) isolates from an outbreak on Great Nicobar Island, India, in 2022 reveals the involvement of a cluster 2.5 recombinant LSDV strain (East/Southeast Asian lineage).

Sudhakar S, Mishra N, Kalaiyarasu S, Agrawal F, Sanyal A Arch Virol. 2025; 170(4):68.

PMID: 40053157 DOI: 10.1007/s00705-025-06252-2.

Differentially Expressed miRNA Profiles in Serum-Derived Exosomes from Cattle Infected with Lumpy Skin Disease Virus.

Truong A, Tran H, Phan L, Phan T, Chu N, Vu T Pathogens. 2025; 14(2).

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Evaluation of antibody titer and associated risk factors of goat pox vaccine against lumpy skin disease in crossbred buffaloes.

Abulaiti A, Naseer Z, Ahmed Z, Tian S, Liu W, Shoaib M Vet Res Commun. 2025; 49(2):104.

PMID: 39951183 PMC: 11828800. DOI: 10.1007/s11259-025-10673-4.

An evaluation of financial losses due to lumpy skin disease outbreaks in dairy farms of northern Thailand.

Modethed W, Kreausukon K, Singhla T, Boonsri K, Pringproa K, Sthitmatee N Front Vet Sci. 2025; 11:1501460.

PMID: 39926595 PMC: 11804113. DOI: 10.3389/fvets.2024.1501460.

Neethling Strain-Based Homologous Live Attenuated LSDV Vaccines Provide Protection Against Infection with a Clade 2.5 Recombinant LSDV Strain.

Philips W, Haegeman A, Kresic N, Mostin L, de Regge N Vaccines (Basel). 2025; 13(1.

PMID: 39852787 PMC: 11769152. DOI: 10.3390/vaccines13010008.