Negative Pressure Wound Therapy for Skin Necrosis Prevention After Snakebite in the Emergency Department: A Retrospective Cohort Study

Overview

Journal Medicine (Baltimore)

Specialty General Medicine

Date 2021 Feb 6

PMID 33546055

Citations 5

Authors

Kwan Jae Kim

Jin Hong Min

Insool Yoo

Seung Whan Kim

Jinwoong Lee

Seung Ryu

Yeon Ho You

Jung Soo Park

Won Joon Jeong

Yong Chul Cho

Se Kwang Oh

Yong Nam In

Hong Joon Ahn

Chang Shin Kang

Hyunwoo Kyung

Byung Kook Lee

Dong Hun Lee

Dong Hoon Lee

Affiliations

Soon will be listed here.

Abstract

This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.

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