» Articles » PMID: 33542944

Accuracy of the Anatomage Table in Detecting Extranodal Extension in Head and Neck Cancer: a Pilot Study

Overview
Specialty Radiology
Date 2021 Feb 5
PMID 33542944
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

: To assess whether the three-dimensional reconstructions of preoperative computed tomography (CT) scans are helpful for establishing extranodal extension (ENE) in head and neck carcinoma. : Patients with a histological diagnosis of ENE ( ) were considered "cases" and patients with negative histological examination for ENE ( ) were considered "controls." Cases and controls were divided into two groups: a major nodes (MaN) group (lymph nodes on ) and a minor nodes (MiN) group (lymph nodes on ). The preoperative CT scans were uploaded to the Anatomage Table and were randomly and blindly provided to the radiologist for assessment. The findings at the Anatomage Table were compared with those of CT and magnetic resonance imaging (MRI) scans. : Analysis of data from the MaN group showed that the Anatomage Table had a higher percentage of concordance with histopathological examination (90%) than the CT and MRI scans. The Anatomage Table had 100% sensitivity in identifying all patients, associated with a lower specificity. The negative predictive value of 100% allowed identification of patients. In the MiN group, on the other hand, sensitivity was lower, related to a high number of false-negative results. : The Anatomage Table could represent a useful tool for preoperatively establishing the extranodal extension of cervical lymph node metastasis.

Citing Articles

The Holistic Review on Occurrence, Biology, Diagnosis, and Treatment of Oral Squamous Cell Carcinoma.

Alsaeedi S, Aggarwal S Cureus. 2022; 14(10):e30226.

PMID: 36381928 PMC: 9651169. DOI: 10.7759/cureus.30226.


Novel pathological predictive factors for extranodal extension in oral squamous cell carcinoma: a retrospective cohort study based on tumor budding, desmoplastic reaction, tumor-infiltrating lymphocytes, and depth of invasion.

Noda Y, Ishida M, Ueno Y, Fujisawa T, Iwai H, Tsuta K BMC Cancer. 2022; 22(1):402.

PMID: 35418058 PMC: 9006434. DOI: 10.1186/s12885-022-09393-8.


XR (Extended Reality: Virtual Reality, Augmented Reality, Mixed Reality) Technology in Spine Medicine: Status Quo and Quo Vadis.

Morimoto T, Kobayashi T, Hirata H, Otani K, Sugimoto M, Tsukamoto M J Clin Med. 2022; 11(2).

PMID: 35054164 PMC: 8779726. DOI: 10.3390/jcm11020470.


Three-Dimensional Virtual Anatomy as a New Approach for Medical Student's Learning.

Bartoletti-Stella A, Gatta V, Mariani G, Gobbi P, Falconi M, Manzoli L Int J Environ Res Public Health. 2021; 18(24).

PMID: 34948857 PMC: 8702207. DOI: 10.3390/ijerph182413247.


The Impact of Histopathological Features on the Prognosis of Oral Squamous Cell Carcinoma: A Comprehensive Review and Meta-Analysis.

da Silva Dolens E, Dourado M, Almangush A, Salo T, Gurgel Rocha C, da Silva S Front Oncol. 2021; 11:784924.

PMID: 34858861 PMC: 8631280. DOI: 10.3389/fonc.2021.784924.

References
1.
Mu J, Liang X, Li F, Liu J, Zhang S, Tian J . Ultrasound features of extranodal extension in the metastatic cervical lymph nodes of papillary thyroid cancer: a case-control study. Cancer Biol Med. 2018; 15(2):171-177. PMC: 5994548. DOI: 10.20892/j.issn.2095-3941.2017.0092. View

2.
Cybulski A, Catania M, Brancato S, Cogo N, Paola V, Mucelli R . Added value of MRI tractography of peri-prostatic nerve plexus to conventional T2-WI in detection of extra-capsular extension of prostatic cancer. Radiol Med. 2019; 124(10):946-954. DOI: 10.1007/s11547-019-01047-3. View

3.
Faraji F, Aygun N, Coquia S, Gourin C, Tan M, Rooper L . Computed tomography performance in predicting extranodal extension in HPV-positive oropharynx cancer. Laryngoscope. 2019; 130(6):1479-1486. DOI: 10.1002/lary.28237. View

4.
Lim Y, Lee J, Choi E . Perifacial lymph node metastasis in the submandibular triangle of patients with oral and oropharyngeal squamous cell carcinoma with clinically node-positive neck. Laryngoscope. 2006; 116(12):2187-90. DOI: 10.1097/01.mlg.0000244390.40200.e1. View

5.
Marcuzzo A, Suran-Brunelli A, Cin E, Rigo S, Piccinato A, Boscolo Nata F . Surgical Anatomy of the Marginal Mandibular Nerve: A Systematic Review and Meta-Analysis. Clin Anat. 2019; 33(5):739-750. DOI: 10.1002/ca.23497. View