Comparison of Dental Caries (DMFT and DMFS Indices) Between Asthmatic Patients and Control Group in Iran: a Meta-analysis

Overview

Journal Asthma Res Pract

Date 2021 Feb 5

PMID 33541418

Citations 3

Authors

Nadia Elyassi Gorji

Pegah Nasiri

Ali Malekzadeh Shafaroudi

Mahmood Moosazadeh

Affiliations

Soon will be listed here.

Abstract

Background: The association between caries index, which is diagnosed by Decayed, Missing, and Filled Teeth (DMFT), and asthma has been assessed in several studies, which yielded contradictory results. Meta-analysis is the statistical procedure for combining data from multiple studies and reducing the differences among parameters due to the increased number of studies involved in the analysis process. Therefore, the present study aimed to determine the relationship between dental caries using decayed, missing, filled teeth indices (DMFT, dmft, and DMFS indices) and asthma using meta-analysis.

Methods: Databases were searched using such keywords as "Asthma," "Caries," "DMFT," "DMFS," "Iran," and OR operators, AND, and NOT. After the elimination of duplicate documentation, the articles which met the inclusion criteria were selected. Quality assessment was performed based on the Newcastle-Ottawa Quality Checklist (NOS). After that, standardized mean difference (SMD) of DMFT, dmft, and Decayed, Missing, and Filled Surfaces (DMFS) indices were estimated.

Results: The number of 10 evidence was extracted out of nine studies in which mean oral health indices were compared between asthmatic patients and the control group. Out of 10 evidences that examined the association of DMFT, dmft, and DMFS with asthma, these indices were higher in asthmatic patients than the control group in seven cases. In three cases, these differences were statistically significant. The SMD of DMFT, dmft, and DMFS indices between asthmatic patients and the control group at the confidence level of 95% were reported as 0.29 (- 0.05, 0.62), 0.48 (- 0.20, 1.17), and - 0.05(- 0.30, 0.21), respectively.

Conclusion: According to the results, the prevalence of dental caries is higher among patients with asthma than in the control group. Therefore, having asthma could be considered a risk factor for the development of dental caries.

Citing Articles

The relationship between dental caries with asthma, disease duration, and type of medications in the Azar cohort population.

Katebi K, Ashkannejhad S, Mahboobi Z, Faramarzi E, Sharififard N BMC Oral Health. 2024; 24(1):1511.

PMID: 39702119 PMC: 11660791. DOI: 10.1186/s12903-024-05291-6.

Drugs Prescribed for Asthma and Their Adverse Effects on Dental Health.

Pacheco-Quito E, Jaramillo J, Sarmiento-Ordonez J, Cuenca-Leon K Dent J (Basel). 2023; 11(5).

PMID: 37232764 PMC: 10217153. DOI: 10.3390/dj11050113.

Microbiome Analysis of Carious Lesions in Pre-School Children with Early Childhood Caries and Congenital Heart Disease.

Schulz-Weidner N, Weigel M, Turujlija F, Komma K, Mengel J, Schlenz M Microorganisms. 2021; 9(9).

PMID: 34576799 PMC: 8469307. DOI: 10.3390/microorganisms9091904.

References

Shulman J, Taylor S, Nunn M . The association between asthma and dental caries in children and adolescents: A population-based case-control study. Caries Res. 2001; 35(4):240-6. DOI: 10.1159/000047464. View

Kharitonov S, Yates D, Robbins R, Shinebourne E, Barnes P . Increased nitric oxide in exhaled air of asthmatic patients. Lancet. 1994; 343(8890):133-5. DOI: 10.1016/s0140-6736(94)90931-8. View

Shimizu T, Ho B, Deeley K, Briseno-Ruiz J, Faraco Jr I, Schupack B . Enamel formation genes influence enamel microhardness before and after cariogenic challenge. PLoS One. 2012; 7(9):e45022. PMC: 3454391. DOI: 10.1371/journal.pone.0045022. View

Patir A, Seymen F, Yildirim M, Deeley K, Cooper M, Marazita M . Enamel formation genes are associated with high caries experience in Turkish children. Caries Res. 2008; 42(5):394-400. PMC: 2820320. DOI: 10.1159/000154785. View

Rezende G, Dos Santos N, Stein C, Hilgert J, Faustino-Silva D . Asthma and oral changes in children: Associated factors in a community of southern Brazil. Int J Paediatr Dent. 2019; 29(4):456-463. DOI: 10.1111/ipd.12487. View

Tarraf H, Aydin O, Mungan D, AlBader M, Mahboub B, Doble A . Prevalence of asthma among the adult general population of five Middle Eastern countries: results of the SNAPSHOT program. BMC Pulm Med. 2018; 18(1):68. PMC: 5948696. DOI: 10.1186/s12890-018-0621-9. View

Ehsani S, Moin M, Meighani G, Pourhashemi S, Khayatpisheh H, Yarahmadi N . Oral health status in preschool asthmatic children in Iran. Iran J Allergy Asthma Immunol. 2013; 12(3):254-61. View

Meldrum A, Thomson W, Drummond B, Sears M . Is asthma a risk factor for dental caries? Finding from a cohort study. Caries Res. 2001; 35(4):235-9. DOI: 10.1159/000047463. View

Ergoz N, Seymen F, Gencay K, Tamay Z, Deeley K, Vinski S . Genetic variation in Ameloblastin is associated with caries in asthmatic children. Eur Arch Paediatr Dent. 2013; 15(3):211-6. PMC: 4014527. DOI: 10.1007/s40368-013-0096-6. View

10.

Flexeder C, Kabary Hassan L, Standl M, Schulz H, Kuhnisch J . Is There an Association between Asthma and Dental Caries and Molar Incisor Hypomineralisation?. Caries Res. 2019; 54(1):87-95. DOI: 10.1159/000504382. View

11.

Bahrololoomi Z, Bemanian M, Ghaffourifard R, Ahmadi B . Effect of inhaled medication on dental caries index in asthmatic children. Allergol Immunopathol (Madr). 2018; 46(2):196-200. DOI: 10.1016/j.aller.2017.09.019. View

12.

Simpson A, John S, Jury F, Niven R, Woodcock A, Ollier W . Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment. Am J Respir Crit Care Med. 2006; 174(4):386-92. DOI: 10.1164/rccm.200509-1380OC. View

13.

Deeley K, Letra A, ROSE E, Brandon C, Resick J, Marazita M . Possible association of amelogenin to high caries experience in a Guatemalan-Mayan population. Caries Res. 2007; 42(1):8-13. PMC: 2814012. DOI: 10.1159/000111744. View

14.

EMSLIE R, MASSLER M, ZWEMER J . Mouth breathing. I. Etiology and effects; a review. J Am Dent Assoc. 1952; 44(5):506-21. DOI: 10.14219/jada.archive.1952.0099. View

15.

Upham J, Chung L . Optimising treatment for severe asthma. Med J Aust. 2018; 209(S2):S22-S27. DOI: 10.5694/mja18.00175. View

16.

OSullivan , Curzon . Drug treatments for asthma may cause erosive tooth damage . BMJ. 1998; 317(7161):820. View

17.

Garg S, Gupta S, Prakash K, Bhatnagar P . Clinical ventilatory functions and immunological studies in bronchial asthma. J Indian Med Assoc. 1991; 89(1):6-9. View

18.

Laajala A, Pesonen P, Anttonen V, Laitala M . Association of Enamel Caries Lesions with Oral Hygiene and DMFT among Adults. Caries Res. 2019; 53(4):475-481. DOI: 10.1159/000497358. View

19.

Yildiz G, Ermis R, Calapoglu N, Celik E, Turel G . Gene-environment Interactions in the Etiology of Dental Caries. J Dent Res. 2015; 95(1):74-9. DOI: 10.1177/0022034515605281. View

20.

Reddy D, M Hegde A, Munshi A . Dental caries status of children with bronchial asthma. J Clin Pediatr Dent. 2003; 27(3):293-5. View