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Heat Inactivation of the Severe Acute Respiratory Syndrome Coronavirus 2

Overview
Journal J Biosaf Biosecur
Date 2021 Feb 1
PMID 33521591
Citations 99
Authors
Christophe Batejat
Quentin Grassin
Jean-Claude Manuguerra
India Leclercq
Affiliations
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Abstract

Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.

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