Detection of Carcinoma in Serous Effusions: a Review

Overview

Journal Am J Cancer Res

Specialty Oncology

Date 2021 Feb 1

PMID 33520359

Citations 4

Authors

Min Li

Lanbo Zhao

Xue Zhou

Kailu Zhang

Panyue Yin

Shuhua Liu

Yuliang Zou

Qiling Li

Affiliations

Soon will be listed here.

Abstract

A malignant serous effusion is one of the most common complications of advanced tumors, indicating a poor prognosis and having a profound impact on diagnosis, treatment, and prognosis. It is of great significance to identify benign and malignant effusions quickly and accurately. Both cellular and non-cellular components in the effusion can be employed for detection, diagnostic methods are necessary to obtain a definite diagnosis and more relevant information such as tumor classification. In this review, we focus on the comparison of several widespread cytological preparation methods, enrichment technology of exfoliated cells, and present tests for serous effusions, mainly including routine and special stains, immunocytochemistry, electron microscopy, enzyme-linked immunosorbent assay, flow cytometry, and molecular analysis.

Citing Articles

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Diagnostic Value of Claudin-4 and EZH2 Immunohistochemistry in Effusion Cytology.

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