Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review

Overview

Journal Intern Med

Specialty General Medicine

Date 2021 Feb 1

PMID 33518567

Citations 3

Authors

Komei Sakata

Jun Kikuchi

Katsura Emoto

Tomomi Kotaki

Yuichiro Ota

Naoshi Nishina

Hironari Hanaoka

Kotaro Otomo

Katsuya Suzuki

Yuko Kaneko

Tsutomu Takeuchi

Affiliations

Soon will be listed here.

Abstract

We herein report a rare case of a 66-year-old man with refractory chylothorax. Although he had been treated with moderate doses of prednisolone (PSL) on suspicion of pleuritis with Sjögren syndrome, the pleural effusion expanded after the reduction of PSL. Further workup including histopathological examinations of pleura led to the diagnosis of IgG4-RD with bilateral chylothorax without any leakage from the thoracic duct. Combination therapy with high-dose PSL plus rituximab successfully decreased the pleural effusion. This is a very rare case of IgG4-related pleuritis with chylothorax and the first report of its successful treatment with rituximab.

Citing Articles

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