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Recent Advances in Functionalization of Plasmonic Nanostructures for Optical Sensing

Overview
Journal Mikrochim Acta
Specialties Biotechnology
Chemistry
Date 2021 Jan 28
PMID 33506310
Citations 9
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Abstract

This review summarizes the progress that has been made in the use of nanostructured SPR-based chemical sensors and biosensors. Following an introduction into the field, a first large section covers principles of nanomaterial-based SPR sensing, mainly on methods using noble metal nanoparticles (spheres, cubes, triangular plates, etc.). The next section covers methods for functionalization of plasmonic nanostructures, with subsections on functionalization using (a) amino acids and proteins; (b) oligonucleotides, (c) organic polymers, and (d) organic compounds. Several tables are presented that give an overview on the wealth of methods and materials published. A concluding section summarizes the current status, addresses current challenges, and gives an outlook on potential future trends. This review is not intended to be a comprehensive compilation of the literature in the field but rather is a systematic overview of the state of the art in surface chemistry of plasmonic nanostructures. The ability of various ligands and receptors for functionalization of nanoparticles as well as their sensing capability is discussed.

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