The Effectiveness of Fluorescent Light Energy As Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial

Overview

Journal Vet Med Int

Publisher Wiley

Specialty Veterinary Medicine

Date 2021 Jan 28

PMID 33505646

Citations 7

Authors

Andrea Marchegiani

Alessandro Fruganti

Andrea Spaterna

Matteo Cerquetella

Adolfo M Tambella

Susan Paterson

Affiliations

Soon will be listed here.

Abstract

A single centre, single-blinded, prospective, randomized, controlled clinical study was conducted to evaluate the effectiveness of twice weekly fluorescent light energy therapy (Phovia™) as adjunct to systemic antibiotics in the management of deep pyoderma in dogs. Dogs with clinical lesions consistent with deep pyoderma, positive bacterial culture, and showing neutrophil engulfing bacteria at cytology were included in the study. Assessments were undertaken weekly for 8 weeks and every 2 weeks thereafter until 12 weeks after enrolment. At each visit, lesions were scored and cytology was conducted to determine a neutrophil engulfing bacteria score. All dogs (Groups A and B) were treated with systemic antibiotic twice daily, and Group B received additionally Phovia twice weekly. Median treatment duration was 11.7 weeks for Group A and 5.7 weeks for Group B. After 8 weeks of treatment, the percentage of dogs that achieved clinical resolution was 35.0% and 88.0% for Groups A and B, respectively. Lesion scores showed highly statistically significant difference in favour of Group B from week 3 to 8, and neutrophil engulfing bacteria scores showed statistical difference from week 2 onwards in favour of Group B. These results indicate that Phovia, when used as an adjunct to systemic antibiotics, can accelerate time to clinical resolution in cases of canine deep pyoderma.

Citing Articles

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A Prospective, Blinded, Open-Label Clinical Trial to Assess the Ability of Fluorescent Light Energy to Enhance Wound Healing after Mastectomy in Female Dogs.

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Exploring fluorescent light energy as management option for canine superficial bacterial folliculitis.

Marchegiani A, Spaterna A, Fruganti A, Cerquetella M Front Vet Sci. 2023; 10:1155105.

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Fluorescent Light Energy in the Management of Multi Drug Resistant Canine Pyoderma: A Prospective Exploratory Study.

Marchegiani A, Fruganti A, Bazzano M, Cerquetella M, Dini F, Spaterna A Pathogens. 2022; 11(10).

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Critically Appraised Topic on Low-Level Laser Therapy (LLLT) in Dogs: An Advisable Treatment for Skin Diseases?.

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